Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00363"
Predicate | Value (sorted: default) |
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rdfs:label |
"Clozapine"
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rdf:type | |
ns1:description |
"A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent. [PubChem]"
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ns1:drugCategory | |
ns1:interactsWith | |
owl:sameAs |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt
The resource appears as object in 119 triples