Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00530"

No prefix for http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/.
PredicateValue (sorted: default)
rdfs:label
"Erlotinib"
rdf:type
ns1:drugs
ns1:description
"Erlotinib hydrochloride (trade name Tarceva, Genentech/OSIP, originally coded as OSI-774) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. Similar to gefitinib, erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. Erlotinib has recently been shown to be a potent inhibitor of JAK2V617F activity. JAK2V617F is a mutant of tyrosine kinase JAK2, is found in most patients with polycythemia vera (PV) and a substantial proportion of patients with idiopathic myelofibrosis or essential thrombocythemia. The study suggests that erlotinib may be used for treatment of JAK2V617F-positive PV and other myeloproliferative disorders."
ns1:drugCategory
?:Protein Kinase Inhibitors
ns1:interactsWith
?:Trastuzumab
?:Erythromycin
?:Nelfinavir
?:Indinavir
?:Ritonavir
?:Voriconazole
?:Rifabutin
?:Telithromycin
?:Ketoconazole
?:Rifampicin
?:Atazanavir
?:Nefazodone
?:Itraconazole
?:Rifapentine
?:Clarithromycin
?:Saquinavir
?:St. John's Wort
?:Troleandomycin
owl:sameAs
?:APRD00951
?:Trastuzumab
?:Erythromycin
?:Nelfinavir
?:Indinavir
?:Ritonavir
?:Erlotinib
?:Voriconazole
?:Rifabutin
?:Telithromycin
?:Ketoconazole
?:Rifampicin
?:Atazanavir
?:Nefazodone
?:Itraconazole
?:Rifapentine
?:Clarithromycin
?:Saquinavir
?:St. John's Wort
?:Troleandomycin
?:DBSALT000064

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt

The resource appears as object in 37 triples

Context graph