Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00612"

Predicate	Value (sorted: default)
rdfs:label	"Bisoprolol"
rdf:type	ns1:drugs
ns1:description	"Bisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension. Bisoprolol is structurally similar to metoprolol, acebutolol and atenolol in that it has two substituents in the <i>para</i> position of the benzene ring. The β1-selectivity of these agents is thought to be due in part to the large substituents in the <i>para</i> position. At lower doses (less than 20 mg daily), bisoprolol selectively blocks cardiac β1-adrenergic receptors with little activity against β2-adrenergic receptors of the lungs and vascular smooth muscle. Receptor selectivity decreases with daily doses of 20 mg or greater. Unlike propranolol and pindolol, bisoprolol does not exhibit membrane-stabilizing or sympathomimetic activity. Bisoprolol possesses a single chiral centre and is administered as a racemic mixture. Only <i>l</i>-bisoprolol exhibits significant β-blocking activity."
ns1:drugCategory	?:Adrenergic beta-1 Receptor Antagonists ?:Antihypertensive Agents ?:Sympatholytics
ns1:interactsWith	?:Insulin Lispro ?:Insulin Glargine ?:Pipobroman ?:Methysergide ?:Disopyramide ?:Lidocaine ?:Dihydroergotamine ?:Indomethacin ?:Treprostinil ?:Acetohexamide ?:Prazosin ?:Piroxicam ?:Clonidine ?:Voriconazole ?:Verapamil ?:Epinephrine ?:Chlorpropamide ?:Ergotamine ?:Orciprenaline ?:Tolazamide ?:Terbutaline ?:Repaglinide ?:Salmeterol ?:Telithromycin ?:Formoterol ?:Salbutamol ?:Glyburide ?:Rifampicin ?:Ibuprofen ?:Isoprenaline ?:Glipizide ?:Gliclazide ?:Tolbutamide ?:Terazosin ?:Ergonovine ?:Fenoterol ?:Glisoxepide ?:Pirbuterol ?:Insulin Aspart ?:Insulin Detemir ?:Insulin Glulisine ?:Procaterol ?:Glycodiazine ?:Indacaterol
owl:sameAs	?:APRD00257 ?:Insulin Lispro ?:Insulin Glargine ?:Pipobroman ?:Methysergide ?:Disopyramide ?:Lidocaine ?:Dihydroergotamine ?:Indomethacin ?:Treprostinil ?:Acetohexamide ?:Prazosin ?:Piroxicam ?:Clonidine ?:Voriconazole ?:Bisoprolol ?:Verapamil ?:Epinephrine ?:Chlorpropamide ?:Ergotamine ?:Orciprenaline ?:Tolazamide ?:Terbutaline ?:Repaglinide ?:Salmeterol ?:Telithromycin ?:Formoterol ?:Salbutamol ?:Glyburide ?:Rifampicin ?:Ibuprofen ?:Isoprenaline ?:Glipizide ?:Gliclazide ?:Tolbutamide ?:Terazosin ?:Ergonovine ?:Fenoterol ?:Glisoxepide ?:Pirbuterol ?:Insulin Aspart ?:Insulin Detemir ?:Insulin Glulisine ?:Potassium ?:Procaterol ?:Calcium ?:Glycodiazine ?:Indacaterol ?:DBSALT001015

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt

The resource appears as object in 91 triples

Context graph