Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00630"

No prefix for http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/.

Predicate	Value (sorted: default)
rdfs:label	"Alendronate"
rdf:type	ns1:drugs
ns1:description	"Alendronate is a nitrogen-containing, second generation bisphosphonate. Bisphosphonates were first used to treat Paget’s disease in 1971. This class of medications is comprised of inorganic pyrophosphate analogues that contain non-hydrolyzable P-C-P bonds. Similar to other bisphosphonates, alendronate has a high affinity for bone mineral and is taken up during osteoclast resorption. Alendronate inhibits farnesyl pyrophosphate synthetase, one of the enzymes in the mevalonic acid pathway involved in producing isoprenoid compounds that are essential for post-translational modification of small guanosine triphosphate (GTP)-binding proteins, such as Rho, Ras and Rab. Inhibition of this process interferes with osteoclast function and survival. Alendronate is used for the treatment of osteoporosis and Paget’s disease. "
ns1:drugCategory	?:Antihypocalcemic Agents ?:Antiresorptives ?:Bisphosphonates ?:Bone Density Conservation Agents
ns1:interactsWith	?:Calcium Acetate ?:Indomethacin ?:Nabumetone ?:Ketorolac ?:Tenoxicam ?:Piroxicam ?:Fenoprofen ?:Diclofenac ?:Flurbiprofen ?:Etodolac ?:Mefenamic acid ?:Naproxen ?:Diflunisal ?:Iron Dextran ?:Oxaprozin ?:Ibuprofen ?:Calcium Chloride ?:Calcium ?:Magnesium ?:Oxyphenbutazone
owl:sameAs	?:APRD00561 ?:Calcium Acetate ?:Indomethacin ?:Nabumetone ?:Ketorolac ?:Tenoxicam ?:Piroxicam ?:Fenoprofen ?:Diclofenac ?:Flurbiprofen ?:Etodolac ?:Mefenamic acid ?:Naproxen ?:Diflunisal ?:Iron Dextran ?:Oxaprozin ?:Ibuprofen ?:Calcium Chloride ?:Calcium ?:Magnesium ?:Oxyphenbutazone ?:DBSALT000315

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt

The resource appears as object in 40 triples

Context graph