Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00678"

Predicate	Value (sorted: default)
rdfs:label	"Losartan"
rdf:type	ns1:drugs
ns1:description	"Losartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. Losartan and its longer acting metabolite, E-3174, lower blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); they compete with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Losartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure. "
ns1:drugCategory	?:Angiotensin II Type 1 Receptor Blockers ?:Angiotensin Receptor Antagonists ?:Anti-Arrhythmia Agents ?:Antihypertensive Agents
ns1:interactsWith	?:Insulin Lispro ?:Indomethacin ?:Treprostinil ?:Triamterene ?:Spironolactone ?:Trandolapril ?:Amiloride ?:Tobramycin ?:Tretinoin ?:Rifampicin ?:Tolbutamide ?:Potassium ?:Lithium ?:Quinupristin ?:Drospirenone
owl:sameAs	?:APRD00052 ?:BE0002638 ?:BE0002793 ?:BE0003541 ?:BE0003677 ?:BE0003678 ?:BE0003679 ?:BE0003680 ?:Insulin Lispro ?:Indomethacin ?:Treprostinil ?:Triamterene ?:Spironolactone ?:Trandolapril ?:Amiloride ?:Losartan ?:Tobramycin ?:Tretinoin ?:Rifampicin ?:Tolbutamide ?:Potassium ?:Lithium ?:Quinupristin ?:Drospirenone ?:Zinc ?:DBMET00009 ?:DBMET00010 ?:DBMET00303 ?:DBSALT000112

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt

The resource appears as object in 32 triples

Context graph