Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01007"

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PredicateValue (sorted: default)
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"Tioconazole"
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ns1:description
"Tioconazole is an antifungal medication of the Imidazole class used to treat infections caused by a fungus or yeast. Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability."
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