Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01281"

No prefix for http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/.
PredicateValue (sorted: default)
rdfs:label
"Abatacept"
rdf:type
ns1:drugs
ns1:description
"Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. It is produced through recombinant DNA technology in mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes. Although approved for the treatment of rheumatoid arthritis, Repligen has entered a slightly different formulation of CTLA4-Ig into clinical trials (RG2077)."
ns1:drugCategory
?:Antirheumatic Agents
?:Immunosuppressive Agents
ns1:interactsWith
?:Trastuzumab
?:Thalidomide
?:golimumab
?:Tofacitinib
?:Certolizumab pegol
owl:sameAs
?:Trastuzumab
?:Thalidomide
?:golimumab
?:Tofacitinib
?:Certolizumab pegol

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt

The resource appears as object in 10 triples

Context graph