Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01359"

Predicate	Value (sorted: default)
rdfs:label	"Penbutolol"
rdf:type	ns1:drugs
ns1:description	"Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the 5-hydroxytryptamine receptor 1A with antagonistic effects. This binding characteristic of penbutolol is being investigated for its implications in Antidepressant Therapy. Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity."
ns1:drugCategory	?:Adrenergic beta-Antagonists ?:Antihypertensive Agents
ns1:interactsWith	?:Insulin Glargine ?:Pipobroman ?:Methysergide ?:Theophylline ?:Disopyramide ?:Lidocaine ?:Dihydroergotamine ?:Indomethacin ?:Treprostinil ?:Digoxin ?:Prazosin ?:Piroxicam ?:Clonidine ?:Epinephrine ?:Chlorpropamide ?:Ergotamine ?:Orciprenaline ?:Terbutaline ?:Repaglinide ?:Methyldopa ?:Formoterol ?:Glyburide ?:Ibuprofen ?:Gliclazide ?:Terazosin ?:Aminophylline ?:Fenoterol ?:Oxtriphylline
owl:sameAs	?:Insulin Glargine ?:Pipobroman ?:Methysergide ?:Theophylline ?:Disopyramide ?:Lidocaine ?:Dihydroergotamine ?:Indomethacin ?:Treprostinil ?:Digoxin ?:Prazosin ?:Piroxicam ?:Clonidine ?:Epinephrine ?:Chlorpropamide ?:Ergotamine ?:Orciprenaline ?:Terbutaline ?:Repaglinide ?:Methyldopa ?:Formoterol ?:Glyburide ?:Ibuprofen ?:Gliclazide ?:Terazosin ?:Aminophylline ?:Fenoterol ?:Oxtriphylline ?:Potassium ?:Penbutolol ?:Calcium ?:DBSALT000137

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt

The resource appears as object in 59 triples

Context graph