Resource Malonic acid

Predicate	Value (sorted: none)
owl:sameAs	?:Caprylic acid
owl:sameAs	?:Malonic acid
owl:sameAs	?:Acetic acid
owl:sameAs	?:Butanoic Acid
ns1:description	" 141-82-2 experimental Michinori Kuraya, "Process for producing acrylic rubber by copolymerizing acrylic ester and malonic acid derivative having active methylene group." U.S. Patent US4154914, issued June, 1963. This compound belongs to the dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. Dicarboxylic Acids and Derivatives Organic Compounds Organic Acids and Derivatives Carboxylic Acids and Derivatives Dicarboxylic Acids and Derivatives Polyamines Enolates Carboxylic Acids enolate polyamine carboxylic acid Malonate Propanedioic acid logP -0.6 ALOGPS logS 0.28 ALOGPS Water Solubility 1.97e+02 g/l ALOGPS logP -0.33 ChemAxon IUPAC Name propanedioic acid ChemAxon Traditional IUPAC Name malonic acid ChemAxon Molecular Weight 104.0615 ChemAxon Monoisotopic Weight 104.010958616 ChemAxon SMILES OC(=O)CC(O)=O ChemAxon Molecular Formula C3H4O4 ChemAxon InChI InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7) ChemAxon InChIKey InChIKey=OFOBLEOULBTSOW-UHFFFAOYSA-N ChemAxon Polar Surface Area (PSA) 74.6 ChemAxon Refractivity 18.99 ChemAxon Polarizability 8.13 ChemAxon Rotatable Bond Count 2 ChemAxon H Bond Acceptor Count 4 ChemAxon H Bond Donor Count 2 ChemAxon pKa (strongest acidic) 2.43 ChemAxon Physiological Charge -2 ChemAxon Number of Rings 0 ChemAxon Bioavailability 1 ChemAxon Rule of Five true ChemAxon Water Solubility 7.63E+005 mg/L (at 25 Â°C) YALKOWSKY,SH & DANNENFELSER,RM (1992) Melting Point 135 dec Â°C PhysProp logP -0.81 HANSCH,C ET AL. (1995) pKa 2.85 (at 25 Â°C) KORTUM,G ET AL (1961) ChEBI 30794 PubChem Compound 867 PubChem Substance 46504875 KEGG Compound C00383 ChemSpider 844 BindingDB 14673 PDB MLA Wikipedia Malonic_acid SMP00456 Fatty Acid Biosynthesis DB00121 Biotin DB02175 Malonic acid DB03017 Lauric Acid DB03166 Acetic acid DB03568 Butanoic Acid DB03600 Decanoic Acid DB04519 Caprylic acid DB04524 Malonyl-Coenzyme A Q13085 P49327 BE0001917 Sigma factor SigB regulation protein RsbQ Bacillus subtilis (strain 168) # Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284 # Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423 unknown Sigma factor SigB regulation protein RsbQ Involved in hydrolase activity Positive regulator required for energy stress activation of the sigma-B transcription factor. Could be required for rsbP phosphatase activity rsbQ Cytoplasmic None 5.01 30020.0 Bacillus subtilis (strain 168) GenBank Gene Database Z94043 GenBank Protein Database 1945717 UniProtKB O07015 UniProt Accession RSBQ_BACSU >Sigma factor sigB regulation protein rsbQ MNEAILSRNHVKVKGSGKASIMFAPGFGCDQSVWNAVAPAFEEDHRVILFDYVGSGHSDL RAYDLNRYQTLDGYAQDVLDVCEALDLKETVFVGHSVGALIGMLASIRRPELFSHLVMVG PSPCYLNDPPEYYGGFEEEQLLGLLEMMEKNYIGWATVFAATVLNQPDRPEIKEELESRF CSTDPVIARQFAKAAFFSDHREDLSKVTVPSLILQCADDIIAPATVGKYMHQHLPYSSLK QMEARGHCPHMSHPDETIQLIGDYLKAHV >810 bp TCACACGTGTGCTTTTAAATAATCGCCGATCAGCTGTATCGTCTCATCTGGATGGCTCAT ATGAGGGCAATGTCCGCGAGCCTCCATTTGTTTCAGACTGCTATAAGGCAGATGCTGATG CATATACTTACCTACTGTTGCAGGTGCGATGATATCATCTGCACATTGGAGAATAAGAGA GGGAACCGTTACCTTCGAAAGATCCTCTCGGTGATCAGAAAAAAACGCCGCTTTCGCGAA TTGGCGGGCAATGACAGGATCAGTAGAACAAAAACGGCTTTCAAGCTCTTCCTTAATTTC AGGCCGATCTGGCTGATTCAGAACGGTTGCCGCAAATACAGTCGCCCAGCCGATATAATT TTTCTCCATCATCTCCAGCAAGCCAAGGAGCTGCTCCTCTTCAAATCCTCCGTAATACTC AGGCGGATCATTCAAATAGCAAGGAGAAGGCCCCACCATCACCAGATGGGAAAAAAGCTC CGGGCGGCGGATGGATGCAAGCATCCCAATCAAGGCCCCGACGGAGTGACCCACAAACAC GGTTTCCTTCAGATCTAAAGCTTCACAAACATCAAGAACATCCTGGGCATAGCCGTCAAG TGTCTGGTAACGATTCAGGTCATATGCGCGCAAATCTGAATGTCCCGAACCGACGTAATC AAATAAAATCACCCGATGATCTTCTTCAAAGGCAGGTGCCACGGCATTCCACACGCTTTG ATCGCATCCAAAACCAGGTGCGAACATGATAGATGCTTTGCCGCTGCCTTTCACCTTCAC ATGATTTCTAGACAAAATCGCTTCGTTCAT PF00561 Abhydrolase_1 function hydrolase activity function catalytic activity process metabolism process cellular metabolism process aromatic compound metabolism process physiological process BE0001513 Aspartate 1-decarboxylase Shigella flexneri # Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284 # Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423 unknown Aspartate 1-decarboxylase Coenzyme transport and metabolism L-aspartate = beta-alanine + CO(2) panD None 6.09 13834.0 Shigella flexneri GenBank Gene Database AE005674 GenBank Protein Database 24050337 UniProtKB P0A793 UniProt Accession PAND_SHIFL Aspartate 1-decarboxylase precursor Aspartate alpha- decarboxylase EC 4.1.1.11 >Aspartate 1-decarboxylase precursor MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAI AAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKA IPVQVA >369 bp TCAAGCAACCTGTACCGGAATCGCTTTCGCGGTACGTTTCATTTCATTGTCGCCTTCAAA ATAGGCGACATTGGGTCGCCAGGTGCGAGCTTCTTCATCTGGCATGGTAACGAAGCTGGC GATGATGACAATATCGCCGACGCTGGCGCAGTGGGCCGCCGCACCGTTAACAGAAATAAT TCTCGAACCGCGTTCTGCCGCGATGGCATAAGTGGAGAAACGCTTGCCGTTGGTGACATT CCAGATATCGATGGCTTCGTTTTCGAGAATACCGGCTGCGTCAAGAAAATCCTGGTCAAT GGCGCAAGAACCTTCATAGTGCAGGTCCGCATGAGTCACTTTCACGCGGTGGAGTTTGCC CTGCAGCAT PF02261 Asp_decarbox function carboxy-lyase activity function aspartate 1-decarboxylase activity function catalytic activity function lyase activity function carbon-carbon lyase activity process amino acid metabolism process amino acid and derivative metabolism process pyruvate family amino acid metabolism process alanine metabolism process physiological process process alanine biosynthesis process metabolism process cellular metabolism BE0000838 Proto-oncogene tyrosine-protein kinase Src Human # Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284 # Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423 # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Proto-oncogene tyrosine-protein kinase Src Involved in protein kinase activity SRC 20q12-q13 None 7.47 59704.0 Human HUGO Gene Nomenclature Committee (HGNC) 11283 GenAtlas SRC GeneCards SRC GenBank Gene Database AL133293 GenBank Protein Database 10635153 UniProtKB P12931 UniProt Accession SRC_HUMAN c- Src EC 2.7.10.2 p60-Src pp60c-src >Proto-oncogene tyrosine-protein kinase Src GSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAEP KLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDW WLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESE TTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLC HRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLK PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYL RLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTA RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERG YRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL >1611 bp ATGGGTAGCAACAAGAGCAAGCCCAAGGATGCCAGCCAGCGGCGCCGCAGCCTGGAGCCC GCCGAGAACGTGCACGGCGCTGGCGGGGGCGCTTTCCCCGCCTCGCAGACCCCCAGCAAG CCAGCCTCGGCCGACGGCCACCGCGGCCCCAGCGCGGCCTTCGCCCCCGCGGCCGCCGAG CCCAAGCTGTTCGGAGGCTTCAACTCCTCGGACACCGTCACCTCCCCGCAGAGGGCGGGC CCGCTGGCCGGTGGAGTGACCACCTTTGTGGCCCTCTATGACTATGAGTCTAGGACGGAG ACAGACCTGTCCTTCAAGAAAGGCGAGCGGCTCCAGATTGTCAACAACACAGAGGGAGAC TGGTGGCTGGCCCACTCGCTCAGCACAGGACAGACAGGCTACATCCCCAGCAACTACGTG GCGCCCTCCGACTCCATCCAGGCTGAGGAGTGGTATTTTGGCAAGATCACCAGACGGGAG TCAGAGCGGTTACTGCTCAATGCAGAGAACCCGAGAGGGACCTTCCTCGTGCGAGAAAGT GAGACCACGAAAGGTGCCTACTGCCTCTCAGTGTCTGACTTCGACAACGCCAAGGGCCTC AACGTGAAGCACTACAAGATCCGCAAGCTGGACAGCGGCGGCTTCTACATCACCTCCCGC ACCCAGTTCAACAGCCTGCAGCAGCTGGTGGCCTACTACTCCAAACACGCCGATGGCCTG TGCCACCGCCTCACCACCGTGTGCCCCACGTCCAAGCCGCAGACTCAGGGCCTGGCCAAG GATGCCTGGGAGATCCCTCGGGAGTCGCTGCGGCTGGAGGTCAAGCTGGGCCAGGGCTGC TTTGGCGAGGTGTGGATGGGGACCTGGAACGGTACCACCAGGGTGGCCATCAAAACCCTG AAGCCTGGCACGATGTCTCCAGAGGCCTTCCTGCAGGAGGCCCAGGTCATGAAGAAGCTG AGGCATGAGAAGCTGGTGCAGTTGTATGCTGTGGTTTCAGAGGAGCCCATTTACATCGTC ACGGAGTACATGAGCAAGGGGAGTTTGCTGGACTTTCTCAAGGGGGAGACAGGCAAGTAC CTGCGGCTGCCTCAGCTGGTGGACATGGCTGCTCAGATCGCCTCAGGCATGGCGTACGTG GAGCGGATGAACTACGTCCACCGGGACCTTCGTGCAGCCAACATCCTGGTGGGAGAGAAC CTGGTGTGCAAAGTGGCGGACTTTGGGCTGGCTCGGCTCATTGAAGACAATGAGTACACG GCGCGGCAAGGTGCCAAATTCCCCATCAAGTGGACGGCTCCAGAAGCTGCCCTCTATGGC CGCTTCACCATCAAGTCGGACGTGTGGTCCTTCGGGATCCTGCTGACTGAGCTCACCACA AAGGGACGGGTGCCCTACCCTGGGATGGTGAACCGCGAGGTGCTGGACCAGGTGGAGCGG GGCTACCGGATGCCCTGCCCGCCGGAGTGTCCCGAGTCCCTGCACGACCTCATGTGCCAG TGCTGGCGGAAGGAGCCTGAGGAGCGGCCCACCTTCGAGTACCTGCAGGCCTTCCTGGAG GACTACTTCACGTCCACCGAGCCCCAGTACCAGCCCGGGGAGAACCTCTAG PF07714 Pkinase_Tyr PF00017 SH2 PF00018 SH3_1 function catalytic activity function protein-tyrosine kinase activity function ATP binding function transferase activity, transferring phosphorus-containing groups function kinase activity function nucleotide binding function protein kinase activity function purine nucleotide binding function adenyl nucleotide binding function binding function transferase activity process physiological process process cellular process process cell communication process metabolism process signal transduction process macromolecule metabolism process biopolymer metabolism process biopolymer modification process protein modification process intracellular signaling cascade process protein amino acid phosphorylation BE0002707 Putative cytochrome P450 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) unknown Putative cytochrome P450 Involved in monooxygenase activity SCO1207 None 5.02 44355.0 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) GenBank Gene Database AL939108 UniProtKB Q9FCA6 UniProt Accession Q9FCA6_STRCO >Putative cytochrome P450 MTEETISQAVPPVRDWPAVDLPGSDFDPVLTELMREGPVTRISLPNGEGWAWLVTRHDDV RLVTNDPRFGREAVMDRQVTRLAPHFIPARGAVGFLDPPDHTRLRRSVAAAFTARGVERV RERSRGMLDELVDAMLRAGPPADLTEAVLSPFPIAVICELMGVPATDRHSMHTWTQLILS SSHGAEVSERAKNEMNAYFSDLIGLRSDSAGEDVTSLLGAAVGRDEITLSEAVGLAVLLQ IGGEAVTNNSGQMFHLLLSRPELAERLRSEPEIRPRAIDELLRWIPHRNAVGLSRIALED VEIKGVRIRAGDAVYVSYLAANRDPEVFPDPDRIDFERSPNPHVSFGFGPHYCPGGMLAR LESELLVDAVLDRVPGLKLAVAPEDVPFKKGALIRGPEALPVTW >1215 bp ATGACTGAAGAAACGATTTCCCAGGCCGTGCCACCCGTCCGGGACTGGCCGGCCGTCGAC CTTCCCGGCAGCGACTTCGACCCGGTGCTGACCGAGCTGATGCGCGAGGGTCCCGTCACC CGGATCTCGCTGCCCAACGGCGAGGGCTGGGCCTGGCTCGTGACCCGCCACGACGACGTC CGCCTGGTCACCAACGACCCCCGGTTCGGGCGCGAGGCCGTCATGGACCGCCAGGTCACC CGGCTGGCCCCGCACTTCATCCCGGCGCGCGGCGCGGTGGGCTTCCTGGACCCGCCCGAC CACACCCGGCTGCGCCGCTCGGTGGCCGCGGCCTTCACCGCGCGGGGCGTGGAGCGGGTG CGCGAGCGGTCCCGGGGCATGCTCGACGAGCTGGTCGACGCCATGCTGAGGGCCGGTCCG CCCGCCGACCTCACCGAGGCGGTGCTGAGCCCGTTCCCCATCGCGGTGATCTGCGAGCTG ATGGGTGTGCCGGCCACCGACCGGCACTCCATGCACACCTGGACCCAGCTGATCCTGTCC TCCTCGCACGGCGCCGAGGTCAGCGAGCGGGCCAAGAACGAGATGAACGCCTACTTCTCG GATCTCATCGGGCTCCGCTCCGACAGCGCGGGCGAGGACGTCACCTCGCTGCTGGGTGCC GCCGTGGGGCGGGACGAGATCACGCTGTCGGAGGCCGTCGGGCTCGCGGTGCTGCTCCAG ATCGGCGGCGAGGCGGTCACCAACAACAGCGGGCAGATGTTCCACCTGCTGCTGAGCCGC CCGGAGCTGGCCGAACGCCTGCGCTCCGAGCCGGAGATCCGCCCCCGGGCCATCGACGAG CTGCTGCGCTGGATCCCGCACCGCAACGCCGTGGGGCTGTCCCGGATCGCCCTGGAGGAC GTGGAGATCAAGGGGGTGCGGATCCGCGCGGGCGACGCCGTCTACGTCTCGTACCTGGCG GCCAACCGCGACCCGGAGGTGTTCCCCGACCCGGACCGCATCGACTTCGAGCGCTCCCCC AACCCGCACGTCTCCTTCGGCTTCGGCCCGCACTACTGTCCCGGCGGCATGCTGGCGCGG CTGGAGTCGGAGCTGCTCGTCGACGCGGTCCTGGACCGCGTGCCGGGGCTGAAGCTCGCG GTGGCGCCGGAGGACGTGCCCTTCAAGAAGGGTGCGCTGATCCGCGGGCCCGAGGCCCTG CCGGTGACGTGGTGA PF00067 p450 function tetrapyrrole binding function catalytic activity function heme binding function monooxygenase activity function oxidoreductase activity function ion binding function cation binding function transition metal ion binding function iron ion binding function binding process metabolism process cellular metabolism process generation of precursor metabolites and energy process electron transport process physiological process BE0002708 U1 small nuclear ribonucleoprotein A Human unknown U1 small nuclear ribonucleoprotein A Involved in nucleotide binding Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process SNRPA 19q13.1 Nucleus None 10.5 31280.0 Human HUGO Gene Nomenclature Committee (HGNC) HGNC:11151 GenAtlas SNRPA GenBank Gene Database M60784 UniProtKB P09012 UniProt Accession SNRPA_HUMAN U1 snRNP protein A U1-A U1A protein >U1 small nuclear ribonucleoprotein A MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFK EVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPA TKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQI PPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLV PGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK >849 bp ATGGCAGTTCCCGAGACCCGCCCTAACCACACTATTTATATCAACAACCTCAATGAGAAG ATCAAGAAGGATGAGCTAAAAAAGTCCCTGTACGCCATCTTCTCCCAGTTTGGCCAGATC CTGGATATCCTGGTATCACGGAGCCTGAAGATGAGGGGCCAGGCCTTTGTCATCTTCAAG GAGGTCAGCAGCGCCACCAACGCCCTGCGCTCCATGCAGGGTTTCCCTTTCTATGACAAA CCTATGCGTATCCAGTATGCCAAGACCGACTCAGATATCATTGCCAAGATGAAAGGCACC TTCGTGGAGCGGGACCGCAAGCGGGAGAAGAGGAAGCCCAAGAGCCAGGAGACCCCGGCC ACCAAGAAGGCTGTGCAAGGCGGGGGAGCCACCCCCGTGGTGGGGGCTGTCCAGGGGCCT GTCCCGGGCATGCCGCCGATGACTCAGGCGCCCCGCATTATGCACCACATGCCGGGCCAG CCGCCCTACATGCCGCCCCCTGGTATGATCCCCCCGCCAGGCCTTGCACCTGGCCAGATC CCACCAGGGGCCATGCCCCCGCAGCAGCTTATGCCAGGACAGATGCCCCCTGCCCAGCCT CTTTCTGAGAATCCACCGAATCACATCTTGTTCCTCACCAACCTGCCAGAGGAGACCAAC GAGCTCATGCTGTCCATGCTTTTCAATCAGTTCCCTGGCTTCAAGGAGGTCCGTCTGGTA CCCGGGCGGCATGACATCGCCTTCGTGGAGTTTGACAATGAGGTACAGGCAGGGGCAGCT CGCGATGCCCTGCAGGGCTTTAAGATCACGCAGAACAACGCCATGAAGATCTCCTTTGCC AAGAAGTAG PF00076 RRM_1 function binding function nucleotide binding function nucleic acid binding BE0002702 Malonamidase E2 Bradyrhizobium japonicum unknown Malonamidase E2 Involved in carbon-nitrogen ligase activity, with glutamine as amido-N-donor Cytoplasmic None 8.13 43682.0 Bradyrhizobium japonicum GenBank Gene Database AF012735 UniProtKB Q9ZIV5 UniProt Accession Q9ZIV5_BRAJP >Malonamidase E2 MISLADLQRRIETGELSPNAAIAQSHAAIEAREKEVHAFVRHDKSARAQASGPLRGIAVG IKDIIDTANMPTEMGSEIYRGWQPRSDAPVVMMLKRAGATIIGKTTTTAFASRDPTATLN PHNTGHSPGGSSSGSAAAVGAGMIPLALGTQTGGSVIRPAAYCGTAAIKPSFRMLPTVGV KCYSWALDTVGLFGARAEDLARGLLAMTGRSEFSGIVPAKAPRIGVVRQEFAGAVEPAAE QGLQAAIKAAERAGASVQAIDLPEAVHEAWRIHPIIQDFEAHRALAWEFSEHHDEIAPML RASLDATVGLTPKEYDEARRIGRRGRRELGEVFEGVDVLLTYSAPGTAPAKALASTGDPR YNRLWTLMGNPCVNVPVLKVGGLPIGVQVIARFGNDAHALATAWFLEDALAKSG >1245 bp ATGATCTCACTCGCCGACCTCCAGCGCCGCATCGAAACGGGCGAGCTGTCGCCTAACGCA GCCATCGCCCAGTCGCACGCGGCGATCGAGGCGCGGGAGAAGGAGGTCCATGCCTTCGTC CGCCACGACAAGTCGGCAAGAGCGCAAGCCTCCGGCCCGCTGCGCGGTATCGCCGTCGGC ATCAAGGACATCATCGACACCGCCAACATGCCCACCGAGATGGGCTCGGAGATCTATCGC GGCTGGCAGCCGCGCAGCGACGCGCCTGTCGTGATGATGCTGAAGCGGGCGGGGGCCACC ATCATCGGCAAGACCACCACCACGGCGTTCGCCTCGCGCGATCCGACGGCGACGCTCAAT CCGCACAATACCGGCCATTCCCCGGGCGGCTCGTCCTCGGGCTCGGCGGCGGCGGTCGGC GCCGGCATGATCCCGCTGGCGCTGGGCACCCAGACCGGCGGCTCGGTGATCCGGCCCGCC GCCTATTGCGGGACGGCCGCGATCAAGCCGTCGTTCCGCATGCTGCCGACGGTCGGCGTG AAGTGCTATTCGTGGGCGCTCGACACGGTCGGCCTGTTCGGCGCGCGCGCGGAGGATCTC GCGCGCGGACTGCTGGCGATGACCGGCCGCAGCGAATTCTCCGGCATCGTCCCGGCCAAG GCACCGCGCATCGGCGTGGTCAGGCAGGAGTTCGCCGGCGCTGTCGAGCCGGCGGCCGAG CAGGGCCTGCAAGCCGCGATCAAGGCGGCCGAGCGGGCCGGGGCCAGTGTTCAGGCCATC GATCTGCCCGAGGCGGTGCATGAGGCCTGGCGCATCCATCCCATCATCCAGGATTTCGAG GCGCATCGCGCGCTCGCCTGGGAGTTTTCCGAGCATCACGACGAGATCGCGCCGATGCTG CGCGCCAGTCTCGATGCGACGGTCGGGCTCACGCCGAAGGAATATGACGAGGCGCGCCGG ATCGGCCGCCGTGGCCGCCGCGAGCTTGGCGAAGTGTTCGAGGGCGTCGACGTGCTCTTG ACCTATTCGGCGCCGGGCACCGCGCCGGCCAAGGCTCTCGCGAGCACCGGCGACCCTCGC TACAACCGGCTCTGGACGCTGATGGGCAATCCTTGCGTCAACGTGCCGGTGCTGAAGGTC GGTGGCCTGCCGATCGGCGTGCAGGTGATCGCGCGCTTCGGCAACGACGCACATGCGCTT GCGACGGCGTGGTTCCTGGAGGATGCGCTGGCGAAATCAGGCTAG PF01425 Amidase function catalytic activity function hydrolase activity function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides function amidase activity BE0002675 Acetyl transferase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) unknown Acetyl transferase Involved in N-acetyltransferase activity rimL None 7.19 20606.0 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GenBank Gene Database AE008771 UniProtKB Q8ZPC0 UniProt Accession Q8ZPC0_SALTY EC 2.3.1.- >Acetyl transferase MVEIIPVSTTLELRAADESHVPALHQLVLKNKAWLQQSLDWPQYVTSQEETRKHVQGNIL LHQRGYAKMYLIFCQNEMAGVLSFNAIEPINKAAYIGYWLDESFQGQGIMSQSLQALMTH YARRGDIRRFVIKCRVDNQASNAVARRNHFTLEGCMKQAEYLNGDYHDVNMYARIIDAD >540 bp TTAATCCGCATCAATAATGCGGGCATACATATTAACGTCGTGATAGTCGCCGTTAAGATA CTCCGCCTGCTTCATACAGCCCTCCAGCGTAAAATGGTTGCGCCGTGCGACTGCGTTACT GGCCTGATTATCAACGCGGCATTTAATGACGAAGCGCCGAATATCGCCGCGCCGGGCATA ATGTGTCATCAGCGCCTGTAATGATTGCGACATTATCCCTTGTCCCTGGAAGGACTCATC CAGCCAGTAACCGATATAGGCGGCTTTGTTTATCGGTTCGATGGCATTAAATGAGAGTAC GCCTGCCATCTCATTCTGGCAGAAAATCAGGTACATTTTGGCGTAACCACGCTGGTGCAA CAGTATATTACCCTGCACATGCTTACGCGTTTCCTCCTGCGACGTGACATATTGCGGCCA GTCGAGCGACTGTTGTAGCCACGCTTTGTTTTTGAGTACCAGTTGGTGCAGCGCCGGAAC ATGACTTTCATCTGCCGCTCGCAGTTCCAGCGTCGTGCTAACAGGAATAATTTCCACCAT PF00583 Acetyltransf_1 function acetyltransferase activity function transferase activity, transferring acyl groups function transferase activity, transferring groups other than amino-acyl groups function acyltransferase activity function N-acetyltransferase activity function catalytic activity function transferase activity "
owl:sameAs	?:Malonyl-Coenzyme A
owl:sameAs	?:Biotin
owl:sameAs	?:Lauric Acid
owl:sameAs	?:Decanoic Acid
rdfs:label	"Malonic acid"
owl:sameAs	?:EXPT02179
rdf:type	ns1:drugs

" 141-82-2 experimental Michinori Kuraya, "Process for producing acrylic rubber by copolymerizing acrylic ester and malonic acid derivative having active methylene group." U.S. Patent US4154914, issued June, 1963. This compound belongs to the dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. Dicarboxylic Acids and Derivatives Organic Compounds Organic Acids and Derivatives Carboxylic Acids and Derivatives Dicarboxylic Acids and Derivatives Polyamines Enolates Carboxylic Acids enolate polyamine carboxylic acid Malonate Propanedioic acid logP -0.6 ALOGPS logS 0.28 ALOGPS Water Solubility 1.97e+02 g/l ALOGPS logP -0.33 ChemAxon IUPAC Name propanedioic acid ChemAxon Traditional IUPAC Name malonic acid ChemAxon Molecular Weight 104.0615 ChemAxon Monoisotopic Weight 104.010958616 ChemAxon SMILES OC(=O)CC(O)=O ChemAxon Molecular Formula C3H4O4 ChemAxon InChI InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7) ChemAxon InChIKey InChIKey=OFOBLEOULBTSOW-UHFFFAOYSA-N ChemAxon Polar Surface Area (PSA) 74.6 ChemAxon Refractivity 18.99 ChemAxon Polarizability 8.13 ChemAxon Rotatable Bond Count 2 ChemAxon H Bond Acceptor Count 4 ChemAxon H Bond Donor Count 2 ChemAxon pKa (strongest acidic) 2.43 ChemAxon Physiological Charge -2 ChemAxon Number of Rings 0 ChemAxon Bioavailability 1 ChemAxon Rule of Five true ChemAxon Water Solubility 7.63E+005 mg/L (at 25 Â°C) YALKOWSKY,SH & DANNENFELSER,RM (1992) Melting Point 135 dec Â°C PhysProp logP -0.81 HANSCH,C ET AL. (1995) pKa 2.85 (at 25 Â°C) KORTUM,G ET AL (1961) ChEBI 30794 PubChem Compound 867 PubChem Substance 46504875 KEGG Compound C00383 ChemSpider 844 BindingDB 14673 PDB MLA Wikipedia Malonic_acid SMP00456 Fatty Acid Biosynthesis DB00121 Biotin DB02175 Malonic acid DB03017 Lauric Acid DB03166 Acetic acid DB03568 Butanoic Acid DB03600 Decanoic Acid DB04519 Caprylic acid DB04524 Malonyl-Coenzyme A Q13085 P49327 BE0001917 Sigma factor SigB regulation protein RsbQ Bacillus subtilis (strain 168) # Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284 # Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423 unknown Sigma factor SigB regulation protein RsbQ Involved in hydrolase activity Positive regulator required for energy stress activation of the sigma-B transcription factor. Could be required for rsbP phosphatase activity rsbQ Cytoplasmic None 5.01 30020.0 Bacillus subtilis (strain 168) GenBank Gene Database Z94043 GenBank Protein Database 1945717 UniProtKB O07015 UniProt Accession RSBQ_BACSU >Sigma factor sigB regulation protein rsbQ MNEAILSRNHVKVKGSGKASIMFAPGFGCDQSVWNAVAPAFEEDHRVILFDYVGSGHSDL RAYDLNRYQTLDGYAQDVLDVCEALDLKETVFVGHSVGALIGMLASIRRPELFSHLVMVG PSPCYLNDPPEYYGGFEEEQLLGLLEMMEKNYIGWATVFAATVLNQPDRPEIKEELESRF CSTDPVIARQFAKAAFFSDHREDLSKVTVPSLILQCADDIIAPATVGKYMHQHLPYSSLK QMEARGHCPHMSHPDETIQLIGDYLKAHV >810 bp TCACACGTGTGCTTTTAAATAATCGCCGATCAGCTGTATCGTCTCATCTGGATGGCTCAT ATGAGGGCAATGTCCGCGAGCCTCCATTTGTTTCAGACTGCTATAAGGCAGATGCTGATG CATATACTTACCTACTGTTGCAGGTGCGATGATATCATCTGCACATTGGAGAATAAGAGA GGGAACCGTTACCTTCGAAAGATCCTCTCGGTGATCAGAAAAAAACGCCGCTTTCGCGAA TTGGCGGGCAATGACAGGATCAGTAGAACAAAAACGGCTTTCAAGCTCTTCCTTAATTTC AGGCCGATCTGGCTGATTCAGAACGGTTGCCGCAAATACAGTCGCCCAGCCGATATAATT TTTCTCCATCATCTCCAGCAAGCCAAGGAGCTGCTCCTCTTCAAATCCTCCGTAATACTC AGGCGGATCATTCAAATAGCAAGGAGAAGGCCCCACCATCACCAGATGGGAAAAAAGCTC CGGGCGGCGGATGGATGCAAGCATCCCAATCAAGGCCCCGACGGAGTGACCCACAAACAC GGTTTCCTTCAGATCTAAAGCTTCACAAACATCAAGAACATCCTGGGCATAGCCGTCAAG TGTCTGGTAACGATTCAGGTCATATGCGCGCAAATCTGAATGTCCCGAACCGACGTAATC AAATAAAATCACCCGATGATCTTCTTCAAAGGCAGGTGCCACGGCATTCCACACGCTTTG ATCGCATCCAAAACCAGGTGCGAACATGATAGATGCTTTGCCGCTGCCTTTCACCTTCAC ATGATTTCTAGACAAAATCGCTTCGTTCAT PF00561 Abhydrolase_1 function hydrolase activity function catalytic activity process metabolism process cellular metabolism process aromatic compound metabolism process physiological process BE0001513 Aspartate 1-decarboxylase Shigella flexneri # Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284 # Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423 unknown Aspartate 1-decarboxylase Coenzyme transport and metabolism L-aspartate = beta-alanine + CO(2) panD None 6.09 13834.0 Shigella flexneri GenBank Gene Database AE005674 GenBank Protein Database 24050337 UniProtKB P0A793 UniProt Accession PAND_SHIFL Aspartate 1-decarboxylase precursor Aspartate alpha- decarboxylase EC 4.1.1.11 >Aspartate 1-decarboxylase precursor MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAI AAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKA IPVQVA >369 bp TCAAGCAACCTGTACCGGAATCGCTTTCGCGGTACGTTTCATTTCATTGTCGCCTTCAAA ATAGGCGACATTGGGTCGCCAGGTGCGAGCTTCTTCATCTGGCATGGTAACGAAGCTGGC GATGATGACAATATCGCCGACGCTGGCGCAGTGGGCCGCCGCACCGTTAACAGAAATAAT TCTCGAACCGCGTTCTGCCGCGATGGCATAAGTGGAGAAACGCTTGCCGTTGGTGACATT CCAGATATCGATGGCTTCGTTTTCGAGAATACCGGCTGCGTCAAGAAAATCCTGGTCAAT GGCGCAAGAACCTTCATAGTGCAGGTCCGCATGAGTCACTTTCACGCGGTGGAGTTTGCC CTGCAGCAT PF02261 Asp_decarbox function carboxy-lyase activity function aspartate 1-decarboxylase activity function catalytic activity function lyase activity function carbon-carbon lyase activity process amino acid metabolism process amino acid and derivative metabolism process pyruvate family amino acid metabolism process alanine metabolism process physiological process process alanine biosynthesis process metabolism process cellular metabolism BE0000838 Proto-oncogene tyrosine-protein kinase Src Human # Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284 # Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423 # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Proto-oncogene tyrosine-protein kinase Src Involved in protein kinase activity SRC 20q12-q13 None 7.47 59704.0 Human HUGO Gene Nomenclature Committee (HGNC) 11283 GenAtlas SRC GeneCards SRC GenBank Gene Database AL133293 GenBank Protein Database 10635153 UniProtKB P12931 UniProt Accession SRC_HUMAN c- Src EC 2.7.10.2 p60-Src pp60c-src >Proto-oncogene tyrosine-protein kinase Src GSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAEP KLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDW WLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESE TTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLC HRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLK PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYL RLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTA RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERG YRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL >1611 bp ATGGGTAGCAACAAGAGCAAGCCCAAGGATGCCAGCCAGCGGCGCCGCAGCCTGGAGCCC GCCGAGAACGTGCACGGCGCTGGCGGGGGCGCTTTCCCCGCCTCGCAGACCCCCAGCAAG CCAGCCTCGGCCGACGGCCACCGCGGCCCCAGCGCGGCCTTCGCCCCCGCGGCCGCCGAG CCCAAGCTGTTCGGAGGCTTCAACTCCTCGGACACCGTCACCTCCCCGCAGAGGGCGGGC CCGCTGGCCGGTGGAGTGACCACCTTTGTGGCCCTCTATGACTATGAGTCTAGGACGGAG ACAGACCTGTCCTTCAAGAAAGGCGAGCGGCTCCAGATTGTCAACAACACAGAGGGAGAC TGGTGGCTGGCCCACTCGCTCAGCACAGGACAGACAGGCTACATCCCCAGCAACTACGTG GCGCCCTCCGACTCCATCCAGGCTGAGGAGTGGTATTTTGGCAAGATCACCAGACGGGAG TCAGAGCGGTTACTGCTCAATGCAGAGAACCCGAGAGGGACCTTCCTCGTGCGAGAAAGT GAGACCACGAAAGGTGCCTACTGCCTCTCAGTGTCTGACTTCGACAACGCCAAGGGCCTC AACGTGAAGCACTACAAGATCCGCAAGCTGGACAGCGGCGGCTTCTACATCACCTCCCGC ACCCAGTTCAACAGCCTGCAGCAGCTGGTGGCCTACTACTCCAAACACGCCGATGGCCTG TGCCACCGCCTCACCACCGTGTGCCCCACGTCCAAGCCGCAGACTCAGGGCCTGGCCAAG GATGCCTGGGAGATCCCTCGGGAGTCGCTGCGGCTGGAGGTCAAGCTGGGCCAGGGCTGC TTTGGCGAGGTGTGGATGGGGACCTGGAACGGTACCACCAGGGTGGCCATCAAAACCCTG AAGCCTGGCACGATGTCTCCAGAGGCCTTCCTGCAGGAGGCCCAGGTCATGAAGAAGCTG AGGCATGAGAAGCTGGTGCAGTTGTATGCTGTGGTTTCAGAGGAGCCCATTTACATCGTC ACGGAGTACATGAGCAAGGGGAGTTTGCTGGACTTTCTCAAGGGGGAGACAGGCAAGTAC CTGCGGCTGCCTCAGCTGGTGGACATGGCTGCTCAGATCGCCTCAGGCATGGCGTACGTG GAGCGGATGAACTACGTCCACCGGGACCTTCGTGCAGCCAACATCCTGGTGGGAGAGAAC CTGGTGTGCAAAGTGGCGGACTTTGGGCTGGCTCGGCTCATTGAAGACAATGAGTACACG GCGCGGCAAGGTGCCAAATTCCCCATCAAGTGGACGGCTCCAGAAGCTGCCCTCTATGGC CGCTTCACCATCAAGTCGGACGTGTGGTCCTTCGGGATCCTGCTGACTGAGCTCACCACA AAGGGACGGGTGCCCTACCCTGGGATGGTGAACCGCGAGGTGCTGGACCAGGTGGAGCGG GGCTACCGGATGCCCTGCCCGCCGGAGTGTCCCGAGTCCCTGCACGACCTCATGTGCCAG TGCTGGCGGAAGGAGCCTGAGGAGCGGCCCACCTTCGAGTACCTGCAGGCCTTCCTGGAG GACTACTTCACGTCCACCGAGCCCCAGTACCAGCCCGGGGAGAACCTCTAG PF07714 Pkinase_Tyr PF00017 SH2 PF00018 SH3_1 function catalytic activity function protein-tyrosine kinase activity function ATP binding function transferase activity, transferring phosphorus-containing groups function kinase activity function nucleotide binding function protein kinase activity function purine nucleotide binding function adenyl nucleotide binding function binding function transferase activity process physiological process process cellular process process cell communication process metabolism process signal transduction process macromolecule metabolism process biopolymer metabolism process biopolymer modification process protein modification process intracellular signaling cascade process protein amino acid phosphorylation BE0002707 Putative cytochrome P450 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) unknown Putative cytochrome P450 Involved in monooxygenase activity SCO1207 None 5.02 44355.0 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) GenBank Gene Database AL939108 UniProtKB Q9FCA6 UniProt Accession Q9FCA6_STRCO >Putative cytochrome P450 MTEETISQAVPPVRDWPAVDLPGSDFDPVLTELMREGPVTRISLPNGEGWAWLVTRHDDV RLVTNDPRFGREAVMDRQVTRLAPHFIPARGAVGFLDPPDHTRLRRSVAAAFTARGVERV RERSRGMLDELVDAMLRAGPPADLTEAVLSPFPIAVICELMGVPATDRHSMHTWTQLILS SSHGAEVSERAKNEMNAYFSDLIGLRSDSAGEDVTSLLGAAVGRDEITLSEAVGLAVLLQ IGGEAVTNNSGQMFHLLLSRPELAERLRSEPEIRPRAIDELLRWIPHRNAVGLSRIALED VEIKGVRIRAGDAVYVSYLAANRDPEVFPDPDRIDFERSPNPHVSFGFGPHYCPGGMLAR LESELLVDAVLDRVPGLKLAVAPEDVPFKKGALIRGPEALPVTW >1215 bp ATGACTGAAGAAACGATTTCCCAGGCCGTGCCACCCGTCCGGGACTGGCCGGCCGTCGAC CTTCCCGGCAGCGACTTCGACCCGGTGCTGACCGAGCTGATGCGCGAGGGTCCCGTCACC CGGATCTCGCTGCCCAACGGCGAGGGCTGGGCCTGGCTCGTGACCCGCCACGACGACGTC CGCCTGGTCACCAACGACCCCCGGTTCGGGCGCGAGGCCGTCATGGACCGCCAGGTCACC CGGCTGGCCCCGCACTTCATCCCGGCGCGCGGCGCGGTGGGCTTCCTGGACCCGCCCGAC CACACCCGGCTGCGCCGCTCGGTGGCCGCGGCCTTCACCGCGCGGGGCGTGGAGCGGGTG CGCGAGCGGTCCCGGGGCATGCTCGACGAGCTGGTCGACGCCATGCTGAGGGCCGGTCCG CCCGCCGACCTCACCGAGGCGGTGCTGAGCCCGTTCCCCATCGCGGTGATCTGCGAGCTG ATGGGTGTGCCGGCCACCGACCGGCACTCCATGCACACCTGGACCCAGCTGATCCTGTCC TCCTCGCACGGCGCCGAGGTCAGCGAGCGGGCCAAGAACGAGATGAACGCCTACTTCTCG GATCTCATCGGGCTCCGCTCCGACAGCGCGGGCGAGGACGTCACCTCGCTGCTGGGTGCC GCCGTGGGGCGGGACGAGATCACGCTGTCGGAGGCCGTCGGGCTCGCGGTGCTGCTCCAG ATCGGCGGCGAGGCGGTCACCAACAACAGCGGGCAGATGTTCCACCTGCTGCTGAGCCGC CCGGAGCTGGCCGAACGCCTGCGCTCCGAGCCGGAGATCCGCCCCCGGGCCATCGACGAG CTGCTGCGCTGGATCCCGCACCGCAACGCCGTGGGGCTGTCCCGGATCGCCCTGGAGGAC GTGGAGATCAAGGGGGTGCGGATCCGCGCGGGCGACGCCGTCTACGTCTCGTACCTGGCG GCCAACCGCGACCCGGAGGTGTTCCCCGACCCGGACCGCATCGACTTCGAGCGCTCCCCC AACCCGCACGTCTCCTTCGGCTTCGGCCCGCACTACTGTCCCGGCGGCATGCTGGCGCGG CTGGAGTCGGAGCTGCTCGTCGACGCGGTCCTGGACCGCGTGCCGGGGCTGAAGCTCGCG GTGGCGCCGGAGGACGTGCCCTTCAAGAAGGGTGCGCTGATCCGCGGGCCCGAGGCCCTG CCGGTGACGTGGTGA PF00067 p450 function tetrapyrrole binding function catalytic activity function heme binding function monooxygenase activity function oxidoreductase activity function ion binding function cation binding function transition metal ion binding function iron ion binding function binding process metabolism process cellular metabolism process generation of precursor metabolites and energy process electron transport process physiological process BE0002708 U1 small nuclear ribonucleoprotein A Human unknown U1 small nuclear ribonucleoprotein A Involved in nucleotide binding Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process SNRPA 19q13.1 Nucleus None 10.5 31280.0 Human HUGO Gene Nomenclature Committee (HGNC) HGNC:11151 GenAtlas SNRPA GenBank Gene Database M60784 UniProtKB P09012 UniProt Accession SNRPA_HUMAN U1 snRNP protein A U1-A U1A protein >U1 small nuclear ribonucleoprotein A MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFK EVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPA TKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQI PPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLV PGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK >849 bp ATGGCAGTTCCCGAGACCCGCCCTAACCACACTATTTATATCAACAACCTCAATGAGAAG ATCAAGAAGGATGAGCTAAAAAAGTCCCTGTACGCCATCTTCTCCCAGTTTGGCCAGATC CTGGATATCCTGGTATCACGGAGCCTGAAGATGAGGGGCCAGGCCTTTGTCATCTTCAAG GAGGTCAGCAGCGCCACCAACGCCCTGCGCTCCATGCAGGGTTTCCCTTTCTATGACAAA CCTATGCGTATCCAGTATGCCAAGACCGACTCAGATATCATTGCCAAGATGAAAGGCACC TTCGTGGAGCGGGACCGCAAGCGGGAGAAGAGGAAGCCCAAGAGCCAGGAGACCCCGGCC ACCAAGAAGGCTGTGCAAGGCGGGGGAGCCACCCCCGTGGTGGGGGCTGTCCAGGGGCCT GTCCCGGGCATGCCGCCGATGACTCAGGCGCCCCGCATTATGCACCACATGCCGGGCCAG CCGCCCTACATGCCGCCCCCTGGTATGATCCCCCCGCCAGGCCTTGCACCTGGCCAGATC CCACCAGGGGCCATGCCCCCGCAGCAGCTTATGCCAGGACAGATGCCCCCTGCCCAGCCT CTTTCTGAGAATCCACCGAATCACATCTTGTTCCTCACCAACCTGCCAGAGGAGACCAAC GAGCTCATGCTGTCCATGCTTTTCAATCAGTTCCCTGGCTTCAAGGAGGTCCGTCTGGTA CCCGGGCGGCATGACATCGCCTTCGTGGAGTTTGACAATGAGGTACAGGCAGGGGCAGCT CGCGATGCCCTGCAGGGCTTTAAGATCACGCAGAACAACGCCATGAAGATCTCCTTTGCC AAGAAGTAG PF00076 RRM_1 function binding function nucleotide binding function nucleic acid binding BE0002702 Malonamidase E2 Bradyrhizobium japonicum unknown Malonamidase E2 Involved in carbon-nitrogen ligase activity, with glutamine as amido-N-donor Cytoplasmic None 8.13 43682.0 Bradyrhizobium japonicum GenBank Gene Database AF012735 UniProtKB Q9ZIV5 UniProt Accession Q9ZIV5_BRAJP >Malonamidase E2 MISLADLQRRIETGELSPNAAIAQSHAAIEAREKEVHAFVRHDKSARAQASGPLRGIAVG IKDIIDTANMPTEMGSEIYRGWQPRSDAPVVMMLKRAGATIIGKTTTTAFASRDPTATLN PHNTGHSPGGSSSGSAAAVGAGMIPLALGTQTGGSVIRPAAYCGTAAIKPSFRMLPTVGV KCYSWALDTVGLFGARAEDLARGLLAMTGRSEFSGIVPAKAPRIGVVRQEFAGAVEPAAE QGLQAAIKAAERAGASVQAIDLPEAVHEAWRIHPIIQDFEAHRALAWEFSEHHDEIAPML RASLDATVGLTPKEYDEARRIGRRGRRELGEVFEGVDVLLTYSAPGTAPAKALASTGDPR YNRLWTLMGNPCVNVPVLKVGGLPIGVQVIARFGNDAHALATAWFLEDALAKSG >1245 bp ATGATCTCACTCGCCGACCTCCAGCGCCGCATCGAAACGGGCGAGCTGTCGCCTAACGCA GCCATCGCCCAGTCGCACGCGGCGATCGAGGCGCGGGAGAAGGAGGTCCATGCCTTCGTC CGCCACGACAAGTCGGCAAGAGCGCAAGCCTCCGGCCCGCTGCGCGGTATCGCCGTCGGC ATCAAGGACATCATCGACACCGCCAACATGCCCACCGAGATGGGCTCGGAGATCTATCGC GGCTGGCAGCCGCGCAGCGACGCGCCTGTCGTGATGATGCTGAAGCGGGCGGGGGCCACC ATCATCGGCAAGACCACCACCACGGCGTTCGCCTCGCGCGATCCGACGGCGACGCTCAAT CCGCACAATACCGGCCATTCCCCGGGCGGCTCGTCCTCGGGCTCGGCGGCGGCGGTCGGC GCCGGCATGATCCCGCTGGCGCTGGGCACCCAGACCGGCGGCTCGGTGATCCGGCCCGCC GCCTATTGCGGGACGGCCGCGATCAAGCCGTCGTTCCGCATGCTGCCGACGGTCGGCGTG AAGTGCTATTCGTGGGCGCTCGACACGGTCGGCCTGTTCGGCGCGCGCGCGGAGGATCTC GCGCGCGGACTGCTGGCGATGACCGGCCGCAGCGAATTCTCCGGCATCGTCCCGGCCAAG GCACCGCGCATCGGCGTGGTCAGGCAGGAGTTCGCCGGCGCTGTCGAGCCGGCGGCCGAG CAGGGCCTGCAAGCCGCGATCAAGGCGGCCGAGCGGGCCGGGGCCAGTGTTCAGGCCATC GATCTGCCCGAGGCGGTGCATGAGGCCTGGCGCATCCATCCCATCATCCAGGATTTCGAG GCGCATCGCGCGCTCGCCTGGGAGTTTTCCGAGCATCACGACGAGATCGCGCCGATGCTG CGCGCCAGTCTCGATGCGACGGTCGGGCTCACGCCGAAGGAATATGACGAGGCGCGCCGG ATCGGCCGCCGTGGCCGCCGCGAGCTTGGCGAAGTGTTCGAGGGCGTCGACGTGCTCTTG ACCTATTCGGCGCCGGGCACCGCGCCGGCCAAGGCTCTCGCGAGCACCGGCGACCCTCGC TACAACCGGCTCTGGACGCTGATGGGCAATCCTTGCGTCAACGTGCCGGTGCTGAAGGTC GGTGGCCTGCCGATCGGCGTGCAGGTGATCGCGCGCTTCGGCAACGACGCACATGCGCTT GCGACGGCGTGGTTCCTGGAGGATGCGCTGGCGAAATCAGGCTAG PF01425 Amidase function catalytic activity function hydrolase activity function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides function amidase activity BE0002675 Acetyl transferase Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) unknown Acetyl transferase Involved in N-acetyltransferase activity rimL None 7.19 20606.0 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GenBank Gene Database AE008771 UniProtKB Q8ZPC0 UniProt Accession Q8ZPC0_SALTY EC 2.3.1.- >Acetyl transferase MVEIIPVSTTLELRAADESHVPALHQLVLKNKAWLQQSLDWPQYVTSQEETRKHVQGNIL LHQRGYAKMYLIFCQNEMAGVLSFNAIEPINKAAYIGYWLDESFQGQGIMSQSLQALMTH YARRGDIRRFVIKCRVDNQASNAVARRNHFTLEGCMKQAEYLNGDYHDVNMYARIIDAD >540 bp TTAATCCGCATCAATAATGCGGGCATACATATTAACGTCGTGATAGTCGCCGTTAAGATA CTCCGCCTGCTTCATACAGCCCTCCAGCGTAAAATGGTTGCGCCGTGCGACTGCGTTACT GGCCTGATTATCAACGCGGCATTTAATGACGAAGCGCCGAATATCGCCGCGCCGGGCATA ATGTGTCATCAGCGCCTGTAATGATTGCGACATTATCCCTTGTCCCTGGAAGGACTCATC CAGCCAGTAACCGATATAGGCGGCTTTGTTTATCGGTTCGATGGCATTAAATGAGAGTAC GCCTGCCATCTCATTCTGGCAGAAAATCAGGTACATTTTGGCGTAACCACGCTGGTGCAA CAGTATATTACCCTGCACATGCTTACGCGTTTCCTCCTGCGACGTGACATATTGCGGCCA GTCGAGCGACTGTTGTAGCCACGCTTTGTTTTTGAGTACCAGTTGGTGCAGCGCCGGAAC ATGACTTTCATCTGCCGCTCGCAGTTCCAGCGTCGTGCTAACAGGAATAATTTCCACCAT PF00583 Acetyltransf_1 function acetyltransferase activity function transferase activity, transferring acyl groups function transferase activity, transferring groups other than amino-acyl groups function acyltransferase activity function N-acetyltransferase activity function catalytic activity function transferase activity "

owl:sameAs

?:Biotin

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