Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB02751"
| Predicate | Value (sorted: none) |
|---|---|
| rdf:type | |
| ns1:description |
"
experimental
This compound belongs to the alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.
Alpha Amino Acids and Derivatives
Organic Compounds
Organic Acids and Derivatives
Carboxylic Acids and Derivatives
Amino Acids, Peptides, and Analogues
Guanidines
Enolates
Polyamines
Carboxylic Acids
Amidines
guanidine
enolate
carboxylic acid
amidine
polyamine
amine
organonitrogen compound
Affinity Labels
logP
-1.8
ALOGPS
logS
-1.4
ALOGPS
Water Solubility
4.19e+00 g/l
ALOGPS
logP
-3.1
ChemAxon
IUPAC Name
2-carbamimidamidoacetic acid
ChemAxon
Traditional IUPAC Name
glycocyamine
ChemAxon
Molecular Weight
117.1066
ChemAxon
Monoisotopic Weight
117.053826483
ChemAxon
SMILES
NC(=N)NCC(O)=O
ChemAxon
Molecular Formula
C3H7N3O2
ChemAxon
InChI
InChI=1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)
ChemAxon
InChIKey
InChIKey=BPMFZUMJYQTVII-UHFFFAOYSA-N
ChemAxon
Polar Surface Area (PSA)
99.2
ChemAxon
Refractivity
36.72
ChemAxon
Polarizability
10.45
ChemAxon
Rotatable Bond Count
2
ChemAxon
H Bond Acceptor Count
5
ChemAxon
H Bond Donor Count
4
ChemAxon
pKa (strongest acidic)
3.37
ChemAxon
pKa (strongest basic)
12.24
ChemAxon
Physiological Charge
0
ChemAxon
Number of Rings
0
ChemAxon
Bioavailability
1
ChemAxon
Rule of Five
true
ChemAxon
PubChem Compound
763
PubChem Substance
46506215
ChemSpider
743
PDB
NMG
BE0000567
Guanidinoacetate N-methyltransferase
Human
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
# Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235
unknown
Guanidinoacetate N-methyltransferase
Involved in methyltransferase activity
GAMT
19p13.3
None
6.09
26318.0
Human
HUGO Gene Nomenclature Committee (HGNC)
HGNC:4136
GenAtlas
GAMT
GeneCards
GAMT
GenBank Gene Database
Z49878
GenBank Protein Database
1212946
UniProtKB
Q14353
UniProt Accession
GAMT_HUMAN
EC 2.1.1.2
>Guanidinoacetate N-methyltransferase
MSAPSATPIFAPGENCSPAWGAAPAAYDAADTHLRILGKPVMERWETPYMHALAAAASSK
GGRVLEVGFGMAIAASKVQEAPIDEHWIIECNDGVFQRLRDWAPRQTHKVIPLKGLWEDV
APTLPDGHFDGILYDTYPLSEETWHTHQFNFIKNHAFRLLKPGGVLTYCNLTSWGELMKS
KYSDITIMFEETQVPALLEAGFRRENIRTEVMALVPPADCRYYAFPQMITPLVTKG
>711 bp
ATGAGCGCCCCCAGCGCGACCCCCATCTTCGCGCCCGGCGAGAACTGCAGCCCCGCGTGG
GGGGCGGCGCCCGCGGCCTACGACGCAGCGGACACGCACCTGCGCATCCTGGGCAAGCCG
GTGATGGAGCGCTGGGAGACCCCCTATATGCACGCGCTGGCCGCCGCCGCCTCCTCCAAA
GGGGGCCGGGTCCTGGAGGTGGGCTTTGGCATGGCCATCGCAGCGTCAAAGGTGCAGGAG
GCGCCCATTGATGAGCATTGGATCATCGAGTGCAATGACGGCGTCTTCCAGCGGCTCCGG
GACTGGGCCCCACGGCAGACACACAAGGTCATCCCCTTGAAAGGCCTGTGGGAGGATGTG
GCACCCACCCTGCCTGACGGTCACTTTGATGGGATCCTGTACGACACGTACCCACTCTCG
GAGGAGACCTGGCACACACACCAGTTCAACTTCATCAAGAACCACGCCTTTCGCCTGCTG
AAGCCGGGGGGCGTCCTCACCTACTGCAACCTCACCTCCTGGGGGGAGCTGATGAAGTCC
AAGTACTCAGACATCACCATCATGTTTGAGGAGACGCAGGTGCCCGCGCTGCTGGAGGCC
GGCTTCCGGAGGGAGAACATCCGTACGGAGGTGATGGCGCTGGTCCCACCGGCCGACTGC
CGCTACTACGCCTTCCCACAGATGATCACGCCCCTGGTGACCAAAGGCTGA
"
|
| owl:sameAs | |
| rdfs:label |
"N-[Amino(Imino)Methyl]Glycine"
|
| ns1:drugCategory |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt
The resource does not appear as an object