Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB03935"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label |
"1,4-Dideoxy-O2-Sulfo-Glucuronic Acid"
|
| rdf:type | |
| ns1:description |
"
experimental
This compound belongs to the pyran carboxylic acids. These are compounds containing a pyran ring which bears a carboxylic acid group.
Pyran Carboxylic Acids
Organic Compounds
Heterocyclic Compounds
Pyrans
Pyran Carboxylic Acids and Derivatives
Sulfuric Acid Monoesters
Oxanes
Secondary Alcohols
Ethers
Polyamines
Enolates
Carboxylic Acids
sulfuric acid monoester
oxane
sulfate-ester
sulfuric acid derivative
secondary alcohol
carboxylic acid derivative
carboxylic acid
enolate
ether
polyamine
alcohol
logP
-1.9
ALOGPS
logS
-0.64
ALOGPS
Water Solubility
5.52e+01 g/l
ALOGPS
logP
-3.4
ChemAxon
IUPAC Name
(2R,4R,5R)-4-hydroxy-5-(sulfooxy)oxane-2-carboxylic acid
ChemAxon
Traditional IUPAC Name
(2R,4R,5R)-4-hydroxy-5-(sulfooxy)oxane-2-carboxylic acid
ChemAxon
Molecular Weight
242.204
ChemAxon
Monoisotopic Weight
242.009637986
ChemAxon
SMILES
O[C@@H]1C[C@@H](OC[C@H]1OS(O)(=O)=O)C(O)=O
ChemAxon
Molecular Formula
C6H10O8S
ChemAxon
InChI
InChI=1S/C6H10O8S/c7-3-1-4(6(8)9)13-2-5(3)14-15(10,11)12/h3-5,7H,1-2H2,(H,8,9)(H,10,11,12)/t3-,4-,5-/m1/s1
ChemAxon
InChIKey
InChIKey=IRTONBQROPNEJZ-UOWFLXDJSA-N
ChemAxon
Polar Surface Area (PSA)
130.36
ChemAxon
Refractivity
43.66
ChemAxon
Polarizability
20.16
ChemAxon
Rotatable Bond Count
3
ChemAxon
H Bond Acceptor Count
7
ChemAxon
H Bond Donor Count
3
ChemAxon
pKa (strongest acidic)
-2
ChemAxon
pKa (strongest basic)
-3.3
ChemAxon
Physiological Charge
-2
ChemAxon
Number of Rings
1
ChemAxon
Bioavailability
1
ChemAxon
Rule of Five
true
ChemAxon
PubChem Compound
46936835
PubChem Substance
46508396
PDB
IDU
BE0001015
Fibroblast growth factor 2
Human
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
unknown
Fibroblast growth factor 2
Involved in growth factor activity
The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors
FGF2
4q26-q27
None
10.01
17254.0
Human
HUGO Gene Nomenclature Committee (HGNC)
HGNC:3676
GenAtlas
FGF2
GeneCards
FGF2
GenBank Gene Database
X04431
GenBank Protein Database
31362
UniProtKB
P09038
UniProt Accession
FGF2_HUMAN
Basic fibroblast growth factor
BFGF
HBGF-2
Heparin-binding growth factor 2 precursor
Prostatropin
>Heparin-binding growth factor 2 precursor
MAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHI
KLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKY
TSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
>468 bp
ATGGCAGCCGGGAGCATCACCACGCTGCCCGCCTTGCCCGAGGATGGCGGCAGCGGCGCC
TTCCCGCCCGGCCACTTCAAGGACCCCAAGCGGCTGTACTGCAAAAACGGGGGCTTCTTC
CTGCGCATCCACCCCGACGGCCGAGTTGACGGGGTCCGGGAGAAGAGCGACCCTCACATC
AAGCTACAACTTCAAGCAGAAGAGAGAGGAGTTGTGTCTATCAAAGGAGTGTGTGCTAAC
CGTTACCTGGCTATGAAGGAAGATGGAAGATTACTGGCTTCTAAATGTGTTACGGATGAG
TGTTTCTTTTTTGAACGATTGGAATCTAATAACTACAATACTTACCGGTCAAGGAAATAC
ACCAGTTGGTATGTGGCACTGAAACGAACTGGGCAGTATAAACTTGGATCCAAAACAGGA
CCTGGGCAGAAAGCTATACTTTTTCTTCCAATGTCTGCTAAGAGCTGA
PF00167
FGF
function
signal transducer activity
function
growth factor activity
function
receptor binding
BE0004149
Annexin A5
Human
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
# Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235
unknown
Annexin A5
ANXA5
Human
UniProtKB
P08758
UniProt Accession
ANXA5_HUMAN
"
|
| owl:sameAs |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt
The resource does not appear as an object