Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB04352"

Predicate	Value (sorted: none)
rdfs:label	"[(2r,3s,4s,5r)-3,4,5-Trihydroxytetrahydrofuran-2-Yl]Methyl Dihydrogen Phosphate"
ns1:description	" experimental This compound belongs to the pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. Pentose Phosphates Organic Compounds Organooxygen Compounds Carbohydrates and Carbohydrate Conjugates Monosaccharides Monosaccharide Phosphates Organophosphate Esters Organic Phosphoric Acids Tetrahydrofurans Oxolanes Secondary Alcohols 1,2-Diols Hemiacetals Polyamines monosaccharide phosphate phosphoric acid ester organic phosphate tetrahydrofuran oxolane polyol hemiacetal 1,2-diol secondary alcohol polyamine ether alcohol logP -2.1 ALOGPS logS -0.84 ALOGPS Water Solubility 3.36e+01 g/l ALOGPS logP -2.4 ChemAxon IUPAC Name {[(2R,3S,4S,5S)-3,4,5-trihydroxyoxolan-2-yl]methoxy}phosphonic acid ChemAxon Traditional IUPAC Name [(2R,3S,4S,5S)-3,4,5-trihydroxyoxolan-2-yl]methoxyphosphonic acid ChemAxon Molecular Weight 230.1098 ChemAxon Monoisotopic Weight 230.01915384 ChemAxon SMILES O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O ChemAxon Molecular Formula C5H11O8P ChemAxon InChI InChI=1S/C5H11O8P/c6-3-2(1-12-14(9,10)11)13-5(8)4(3)7/h2-8H,1H2,(H2,9,10,11)/t2-,3-,4+,5+/m1/s1 ChemAxon InChIKey InChIKey=KTVPXOYAKDPRHY-MBMOQRBOSA-N ChemAxon Polar Surface Area (PSA) 136.68 ChemAxon Refractivity 40.83 ChemAxon Polarizability 18.23 ChemAxon Rotatable Bond Count 3 ChemAxon H Bond Acceptor Count 7 ChemAxon H Bond Donor Count 5 ChemAxon pKa (strongest acidic) 1.22 ChemAxon pKa (strongest basic) -3.7 ChemAxon Physiological Charge -2 ChemAxon Number of Rings 1 ChemAxon Bioavailability 1 ChemAxon Rule of Five true ChemAxon PubChem Compound 46876838 PubChem Substance 46506522 PDB RP5 BE0001942 D-ribose pyranase Bacillus subtilis (strain 168) # Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284 # Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423 unknown D-ribose pyranase Carbohydrate transport and metabolism Involved in the high-affinity ribose membrane transport system rbsD Cell membrane; peripheral membrane protein (Potential) None 4.95 14228.0 Bacillus subtilis (strain 168) GenBank Gene Database Z25798 GenBank Protein Database 397496 UniProtKB P36946 UniProt Accession RBSD_BACSU >High affinity ribose transport protein rbsD MKKHGILNSHLAKILADLGHTDKIVIADAGLPVPDGVLKIDLSLKPGLPAFQDTAAVLAE EMAVEKVIAAAEIKASNQENAKFLENLFSEQEIEYLSHEEFKLLTKDAKAVIRTGEFTPY ANCILQAGVLF >396 bp ATGAAAAAACACGGTATACTGAACAGCCATCTTGCCAAGATTTTAGCCGACCTTGGCCAC ACTGATAAAATTGTCATCGCGGATGCCGGACTGCCGGTTCCTGACGGCGTTTTGAAAATT GATCTTTCACTGAAGCCGGGCCTTCCGGCTTTCCAAGATACAGCGGCAGTACTGGCTGAG GAAATGGCGGTCGAAAAAGTCATTGCTGCAGCTGAAATAAAAGCATCCAATCAGGAGAAT GCGAAATTTCTAGAAAATCTTTTCTCTGAACAAGAGATTGAATACCTTTCTCACGAGGAG TTTAAGCTGCTGACAAAAGATGCAAAGGCAGTCATAAGAACAGGAGAATTCACACCATAT GCCAACTGCATCCTGCAGGCAGGTGTACTTTTCTAG PF05025 RbsD_FucU process transport process carbohydrate transport process physiological process process cellular physiological process BE0001935 ADP-ribose pyrophosphatase, mitochondrial Human # Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284 # Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423 unknown ADP-ribose pyrophosphatase, mitochondrial Involved in hydrolase activity Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'- phosphate NUDT9 4q22.1 Isoform 1:Mitochondrion None 8.45 39125.0 Human HUGO Gene Nomenclature Committee (HGNC) HGNC:8056 GenAtlas NUDT9 GeneCards NUDT9 GenBank Gene Database AY026252 GenBank Protein Database 14160858 UniProtKB Q9BW91 UniProt Accession NUDT9_HUMAN Adenosine diphosphoribose pyrophosphatase ADP-ribose diphosphatase ADP-ribose phosphohydrolase ADP-ribose pyrophosphatase, mitochondrial precursor ADPR-PPase EC 3.6.1.13 Nucleoside diphosphate- linked moiety X motif 9 Nudix motif 9 >ADP-ribose pyrophosphatase, mitochondrial precursor MAGRLLGKALAAVSLSLALASVTIRSSRCRGIQAFRNSFSSSWFHLNTNVMSGSNGSKEN SHNKARTSPYPGSKVERSQVPNEKVGWLVEWQDYKPVEYTAVSVLAGPRWADPQISESNF SPKFNEKDGHVERKSKNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKR DSSGNKIMHPVSGKHILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQ KTSAEKREIEEKLHKLFSQDHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLML EAGDDAGKVKWVDINDKLKLYASHSQFIKLVAEKRDAHWSEDSEADCHAL >1053 bp ATGGCGGGACGCCTCCTGGGAAAGGCTTTAGCCGCGGTGTCTCTCTCTCTGGCCTTGGCC TCTGTGACTATCAGGTCCTCGCGCTGCCGCGGCATCCAGGCGTTCAGAAACTCGTTTTCA TCTTCTTGGTTTCATCTTAATACCAACGTCATGTCTGGTTCTAATGGTTCCAAAGAAAAT TCTCACAATAAGGCTCGGACGTCTCCTTACCCAGGTTCAAAAGTTGAACGAAGCCAGGTT CCTAATGAGAAAGTGGGCTGGCTTGTTGAGTGGCAAGACTATAAGCCTGTGGAATACACT GCAGTCTCTGTCTTGGCTGGACCCAGGTGGGCAGATCCTCAGATCAGTGAAAGTAATTTT TCTCCCAAGTTTAACGAAAAGGATGGGCATGTTGAGAGAAAGAGCAAGAATGGCCTGTAT GAGATTGAAAATGGAAGACCGAGAAATCCTGCAGGACGGACTGGACTGGTGGGCCGGGGG CTTTTGGGGCGATGGGGCCCAAATCACGCTGCAGATCCCATTATAACCAGATGGAAAAGG GATAGCAGTGGAAATAAAATCATGCATCCTGTTTCTGGGAAGCATATCTTACAATTTGTT GCAATAAAAAGGAAAGACTGTGGAGAATGGGCAATCCCAGGGGGGATGGTGGATCCAGGA GAGAAGATTAGTGCCACACTGAAAAGAGAATTTGGTGAGGAAGCTCTCAACTCCTTACAG AAAACCAGTGCTGAGAAGAGAGAAATAGAGGAAAAGTTGCACAAACTCTTCAGCCAAGAC CACCTAGTGATATATAAGGGATATGTTGATGATCCTCGAAACACTGATAATGCATGGATG GAGACAGAAGCTGTGAACTACCATGACGAAACAGGTGAGATAATGGATAATCTTATGCTA GAAGCTGGAGATGATGCTGGAAAAGTGAAATGGGTGGACATCAATGATAAACTGAAGCTT TATGCCAGTCACTCTCAATTCATCAAACTTGTGGCTGAGAAACGAGATGCACACTGGAGC GAGGACTCTGAAGCTGACTGCCATGCGTTGTAG PF00293 NUDIX "
owl:sameAs	?:EXPT02809
rdf:type	ns1:drugs

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt

The resource does not appear as an object

Context graph