Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB05217"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label |
"GMX1777"
|
| rdf:type | |
| ns1:description |
"GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity. In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa B (NF-kB) transcription, resulting in the induction of tumor cell apoptosis."
|
| ns1:drugCategory |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt
The resource does not appear as an object