Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB08747"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label |
"(11R)-10-acetyl-11-(2,4-dichlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one"
|
| rdf:type | |
| ns1:description |
"
experimental
This compound belongs to the benzodiazepines. These are organic compounds containing a benzene ring fused to either isomers of diazepine(unsaturated seven-member heterocycle with two nitrogen atoms replacing two carbon atoms).
Benzodiazepines
Organic Compounds
Heterocyclic Compounds
Benzodiazepines
Dichlorobenzenes
Phenols and Derivatives
Aryl Chlorides
Tertiary Carboxylic Acid Amides
Ketones
Tertiary Amines
Enolates
Enols
Enamines
Polyamines
Carboxylic Acids
Organochlorides
1,3-dichlorobenzene
chlorobenzene
phenol derivative
benzene
aryl halide
aryl chloride
tertiary carboxylic acid amide
carboxamide group
ketone
tertiary amine
enol
enolate
polyamine
carboxylic acid derivative
enamine
carboxylic acid
organohalogen
amine
carbonyl group
organonitrogen compound
organochloride
logP
5.12
ALOGPS
logS
-5.1
ALOGPS
Water Solubility
3.33e-03 g/l
ALOGPS
logP
4.1
ChemAxon
IUPAC Name
(10R)-9-acetyl-10-(2,4-dichlorophenyl)-4-hydroxy-14,14-dimethyl-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7-tetraen-12-one
ChemAxon
Traditional IUPAC Name
(10R)-9-acetyl-10-(2,4-dichlorophenyl)-4-hydroxy-14,14-dimethyl-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7-tetraen-12-one
ChemAxon
Molecular Weight
445.338
ChemAxon
Monoisotopic Weight
444.100747994
ChemAxon
SMILES
[H][C@]1(N(C(C)=O)C2=CC=CC(O)=C2NC2=C1C(=O)CC(C)(C)C2)C1=C(Cl)C=C(Cl)C=C1
ChemAxon
Molecular Formula
C23H22Cl2N2O3
ChemAxon
InChI
InChI=1S/C23H22Cl2N2O3/c1-12(28)27-17-5-4-6-18(29)21(17)26-16-10-23(2,3)11-19(30)20(16)22(27)14-8-7-13(24)9-15(14)25/h4-9,22,26,29H,10-11H2,1-3H3/t22-/m0/s1
ChemAxon
InChIKey
InChIKey=JJTPPGUNMJMPLY-QFIPXVFZSA-N
ChemAxon
Polar Surface Area (PSA)
69.64
ChemAxon
Refractivity
120.12
ChemAxon
Polarizability
44.94
ChemAxon
Rotatable Bond Count
1
ChemAxon
H Bond Acceptor Count
4
ChemAxon
H Bond Donor Count
2
ChemAxon
pKa (strongest acidic)
9.58
ChemAxon
pKa (strongest basic)
-2
ChemAxon
Physiological Charge
0
ChemAxon
Number of Rings
4
ChemAxon
Bioavailability
1
ChemAxon
Rule of Five
true
ChemAxon
Ghose Filter
true
ChemAxon
ChemSpider
24692535
PDB
XND
BE0004389
Genome polyprotein
HCV
# Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235
unknown
Genome polyprotein
Involved in ATP binding
NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication (By similarity)
RNA-directed RNA polymerase:Host endoplasmic reticulum membrane
169-189
359-379
726-746
758-778
783-803
814-834
882-902
929-949
1658-1678
1806-1826
1829-1849
1851-1871
1882-1902
2990-3010
8.17
326763.6
HCV
GenBank Gene Database
D10750
GenBank Protein Database
221607
UniProtKB
O92972
UniProt Accession
POLG_HCVJ4
Capsid protein C
Core protein p19
Core protein p21
Envelope glycoprotein E1
Envelope glycoprotein E2
gp32
gp35
gp68
gp70
Hepacivirin
Non-structural protein 4A
Non-structural protein 4B
Non-structural protein 5A
NS1
NS3P
NS4A
NS4B
NS5A
NS5B
p21
p23
p27
p56
p68
p7
p70
p8
Protease NS2-3
RNA-directed RNA polymerase
Serine protease/NTPase/helicase NS3
>Genome polyprotein
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKASERSQPRG
RRQPIPKARRPEGRAWAQPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPTDPRRRSRNLG
KVIDTLTCGFADLMGYIPLVGAPLGGAARALAHGVRVLEDGVNYATGNLPGCSFSIFLLA
LLSCLTIPASAYEVRNVSGIYHVTNDCSNSSIVYEAADVIMHTPGCVPCVREGNSSRCWV
ALTPTLAARNASVPTTTIRRHVDLLVGTAAFCSAMYVGDLCGSIFLVSQLFTFSPRRHET
VQDCNCSIYPGHVSGHRMAWDMMMNWSPTTALVVSQLLRIPQAVVDMVAGAHWGVLAGLA
YYSMVGNWAKVLIVALLFAGVDGETHTTGRVAGHTTSGFTSLFSSGASQKIQLVNTNGSW
HINRTALNCNDSLQTGFFAALFYAHKFNSSGCPERMASCRPIDWFAQGWGPITYTKPNSS
DQRPYCWHYAPRPCGVVPASQVCGPVYCFTPSPVVVGTTDRSGVPTYSWGENETDVMLLN
NTRPPQGNWFGCTWMNSTGFTKTCGGPPCNIGGVGNRTLICPTDCFRKHPEATYTKCGSG
PWLTPRCLVDYPYRLWHYPCTLNFSIFKVRMYVGGVEHRLNAACNWTRGERCNLEDRDRS
ELSPLLLSTTEWQILPCAFTTLPALSTGLIHLHQNIVDVQYLYGVGSAFVSFAIKWEYIL
LLFLLLADARVCACLWMMLLIAQAEAALENLVVLNAASVAGAHGILSFLVFFCAAWYIKG
RLAPGAAYAFYGVWPLLLLLLALPPRAYALDREMAASCGGAVLVGLVFLTLSPYYKVFLT
RLIWWLQYFITRAEAHMQVWVPPLNVRGGRDAIILLTCAVHPELIFDITKLLLAILGPLM
VLQAGITRVPYFVRAQGLIRACMLVRKVAGGHYVQMAFMKLGALTGTYVYNHLTPLRDWA
HAGLRDLAVAVEPVVFSAMETKVITWGADTAACGDIILGLPVSARRGKEIFLGPADSLEG
QGWRLLAPITAYSQQTRGVLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCINGVCWT
VYHGAGSKTLAGPKGPITQMYTNVDLDLVGWQAPPGARSMTPCSCGSSDLYLVTRHADVI
PVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHVVGVFRAAVCTRGVAKAVDFIPVES
METTMRSPVFTDNSSPPAVPQTFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAA
TLGFGAYMSKAHGIDPNIRTGVRTITTGGSITYSTYGKFLADGGCSGGAYDIIICDECHS
TDSTTILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEIGLSNNGEIPFYGKAI
PIEAIKGGRHLIFCHSKKKCDELAAKLTGLGLNAVAYYRGLDVSVIPPIGDVVVVATDAL
MTGFTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTGRGRSGIYR
FVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSVRLRAYLNTPGLPVCQDHLEFWES
VFTGLTHIDAHFLSQTKQAGDNFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHG
PTPLLYRLGAVQNEVILTHPITKYIMACMSADLEVVTSTWVLVGGVLAALAAYCLTTGSV
VIVGRIILSGKPAVVPDREVLYQEFDEMEECASQLPYIEQGMQLAEQFKQKALGLLQTAT
KQAEAAAPVVESKWRALETFWAKHMWNFISGIQYLAGLSTLPGNPAIASLMAFTASITSP
LTTQNTLLFNILGGWVAAQLAPPSAASAFVGAGIAGAAVGSIGLGKVLVDILAGYGAGVA
GALVAFKVMSGEVPSTEDLVNLLPAILSPGALVVGVVCAAILRRHVGPGEGAVQWMNRLI
AFASRGNHVSPTHYVPESDAAARVTQILSSLTITQLLKRLHQWINEDCSTPCSGSWLRDV
WDWICTVLTDFKTWLQSKLLPRLPGVPFLSCQRGYKGVWRGDGIMQTTCPCGAQIAGHVK
NGSMRIVGPRTCSNTWHGTFPINAYTTGPCTPSPAPNYSRALWRVAAEEYVEVTRVGDFH
YVTGMTTDNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLREDVTFQVGLNQYLVGSQL
PCEPEPDVTVLTSMLTDPSHITAETAKRRLARGSPPSLASSSASQLSAPSLKATCTTHHD
SPDADLIEANLLWRQEMGGNITRVESENKVVILDSFEPLHAEGDEREISVAAEILRKSRK
FPSALPIWARPDYNPPLLESWKDPDYVPPVVHGCPLPPTKAPPIPPPRRKRTVVLTESNV
SSALAELATKTFGSSGSSAVDSGTATALPDLASDDGDKGSDVESYSSMPPLEGEPGDPDL
SDGSWSTVSEEASEDVVCCSMSYTWTGALITPCAAEESKLPINPLSNSLLRHHNMVYATT
SRSASLRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSIEEACKLTPPHSAKSKF
GYGAKDVRNLSSRAVNHIRSVWEDLLEDTETPIDTTIMAKSEVFCVQPEKGGRKPARLIV
FPDLGVRVCEKMALYDVVSTLPQAVMGSSYGFQYSPKQRVEFLVNTWKSKKCPMGFSYDT
RCFDSTVTESDIRVEESIYQCCDLAPEARQAIRSLTERLYIGGPLTNSKGQNCGYRRCRA
SGVLTTSCGNTLTCYLKATAACRAAKLQDCTMLVNGDDLVVICESAGTQEDAAALRAFTE
AMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETAR
HTPINSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQ
IIERLHGLSAFTLHSYSPGEINRVASCLRKLGVPPLRTWRHRARSVRAKLLSQGGRAATC
GRYLFNWAVRTKLKLTPIPAASQLDLSGWFVAGYSGGDIYHSLSRARPRWFPLCLLLLSV
GVGIYLLPNR
>9033 bp
ATGAGCACGAATCCTAAACCTCAAAGAAAAACCAAACGTAACACCAACCGCCGCCCACAG
GACGTCAAGTTCCCGGGCGGTGGTCAGATCGTTGGTGGAGTTTACCTGTTGCCGCGCAGG
GGCCCCAGGTTGGGTGTGCGCGCGACTAGGAAGACTTCCGAGCGGTCGCAACCTCGTGGA
AGGCGACAACCTATCCCAAAGGCTCGCCAACCCGAGGGCAGGGCCTGGGCTCAGCCCGGG
TACCCTTGGCCCCTCTATGGCAATGAGGGCTTGGGGTGGGCAGGATGGCTCCTGTCACCC
CGCGGCTCCCGGCCTAGTTGGGGCCCCACGGACCCCCGGCGTAGGTCGCGTAACTTGGGT
AAGGTCATCGATACCCTTACATGCGGCTTCGCCGATCTCATGGGGTACATTCCGCTCGTC
GGCGCCCCCCTAGGGGGCGCTGCCAGGGCCTTGGCACACGGTGTCCGGGTTCTGGAGGAC
GGCGTGAACTATGCAACAGGGAACTTGCCCGGTTGCTCTTTCTCTATCTTCCTCTTGGCT
CTGCTGTCCTGTTTGACCATCCCAGCTTCCGCTTATGAAGTGCGCAACGTGTCCGGGATA
TACCATGTCACGAACGACTGCTCCAACTCAAGCATTGTGTATGAGGCAGCGGACGTGATC
ATGCATACTCCCGGGTGCGTGCCCTGTGTTCGGGAGGGCAACAGCTCCCGTTGCTGGGTA
GCGCTCACTCCCACGCTCGCGGCCAGAGATGCCAGCGTCCCCACTACGACAATACGACGC
CACGTCGACTTGCTCGTTGGGACGGCTGCTTTCTGCTCCGCTATGTACGTGGGGGATCTC
TGCGGATCTATTTTCCTCGTCTCCCAGCTGTTCACCTTCTCGCCTCGCCGGCATGAGACA
GTGCAGGACTGCAACTGCTCAATCTATCCCGGCCATGTATCAGGTCACCGCATGGCTTGG
GATATGATGATGAACTGGTCACCTACAACAGCCCTAGTGGTGTCGCAGTTGCTCCGGATC
CCACAAGCTGTCGTGGACATGGTGGCGGGGGCCCACTGGGGAGTCCTGGCGGGCCTTGCC
TACTATTCCATGGTAGGGAACTGGGCTAAGGTTCTGATTGTGGCGCTACTCTTTGCCGGC
GTTGACGGGGCGACCTACACGTCGGGGGGGGTGGCCGGCCGCACCACCTCCGGGTTCACG
TCCCTCTTCTCATCTGGGGCGTCTCAGAAAATCCAGCTTGTGAATACCAACGGCAGCTGG
CACATCAACAGGACTGCCCTAAATTGCAATGACTCCCTCCACACTGGGTTCCTTGCCGCG
CTGTTCTACACACACAAGTTCAACTCGTCCGGGTGCCCGGAGCGCATGGCCAGCTGCCGC
CCCATTGACGGGTTCGCCCAGGGATGGGGCCCCATCACCTATACTGAGCCTAACAGCCCG
GATCAGAGGCCTTATTGCTGGCATTACGCGCCTCGACCGTGTGGTATCGTACCCGCGTCG
CAGGTGTGTGGTCCAGTGTATTGTTTCACCCCAAGCCCTGTTGTGGTGGGGACCACCGAT
CGTTCCGGTGTCCCTACGTATAGCTGGGGGGAGAATGAGACAGACGTGATGCTCCTCAAC
AACACGCGTCCGCCACAAGGCAACTGGTTCGGCTGTACATGGATGAATAGTACTGGGTTC
ACTAAGACGTGCGGAGGCCCCCCGTGTAACATCGGGGGGGTCGGTAACCGCACCTTGATC
TGCCCCACGGACTGCTTCCGGAAGCACCCCGAGGCTACTTACACAAAATGTGGCTCGGGG
CCCTGGTTGACACCTAGGTGCCTAGTAGACTACCCATACAGGCTCTGGCACTACCCCTGC
ACTCTCAATTTTTCCATCTTTAAGGTTAGGATGTATGTGGGGGGCGTGGAGCACAGGCTC
AATGCCGCATGCAATTGGACTCGAGGAGAGCGCTGTAACTTGGAGGACAGGGATAGGTCA
GAACTCAGCCCGCTGCTGCTGTCTACAACAGAGTGGCAGATACTGCCCTGTGCCTTCACC
ACCCTACCGGCTTTATCCACTGGTTTGATCCATCTCCATCAGAACATCGTGGACGTGCAA
TACCTGTACGGTGTAGGGTCAGCGTTTGTCTCCTTTGCAATCAAATGGGAGTACATCCTG
TTGCTTTTCCTTCTCCTGGCAGACGCGCGCGTGTGTGCCTGCTTGTGGATGATGCTGCTG
ATAGCCCAGGCTGAGGCCGCCTTAGAGAACTTGGTGGTCCTCAATGCGGCGTCCGTGGCC
GGAGCGCATGGTATTCTCTCCTTTCTTGTGTTCTTCTGCGCCGCCTGGTACATTAAGGGC
AGGCTGGCTCCTGGGGCGGCGTATGCTTTTTATGGCGTATGGCCGCTGCTCCTGCTCCTA
CTGGCGTTACCACCACGAGCTTACGCCTTGGACCGGGAGATGGCTGCATCGTGCGGGGGT
GCGGTTCTTGTAGGTCTGGTATTCTTGACCTTGTCACCATACTACAAAGTGTTTCTCACT
AGGCTCATATGGTGGTTACAATACTTTATCACCAGAGCCGAGGCGCACATGCAAGTGTGG
GTCCCCCCCCTCAACGTTCGGGGAGGCCGCGATGCCATCATCCTCCTCACGTGTGCGGTT
CATCCAGAGTTAATTTTTGACATCACCAAACTCCTGCTCGCCATACTCGGCCCGCTCATG
GTGCTCCAGGCTGGCATAACGAGAGTGCCGTACTTCGTGCGCGCTCAAGGGCTCATTCGT
GCATGCATGTTAGTGCGGAAAGTCGCCGGGGGTCATTATGTCCAAATGGCCTTCATGAAG
CTGGGCGCGCTGACAGGTACGTACGTTTATAACCATCTTACCCCACTGCGGGACTGGGCC
CACGCGGGCCTACGAGACCTTGCGGTGGCGGTAGAGCCCGTCGTCTTCTCCGCCATGGAG
ACCAAGGTCATCACCTGGGGAGCAGACACCGCAGCATGTGGAGACATCATCTTGGGCCTA
CCCGTCTCCGCCCGAAGGGGGAAGGAGATATTTTTGGGACCGGCTGATAGTCTCGAAGGG
CAAGGGTGGCGACTCCTTGCGCCCATCACGGCCTACTCCCAACAAACGCGGGGCGTACTT
GGTTGCATCATCACTAGCCTCACAGGCCGGGACAAGAACCAGGTCGAGGGGGAGGTTCAA
GTGGTTTCTACCGCAACACAATCTTTCCTGGCGACCTGCATCAACGGCGTGTGCTGGACT
GTCTACCATGGCGCTGGCTCGAAGACCCTAGCCGGTCCAAAAGGTCCAATCACCCAAATG
TACACCAATGTAGACCTGGACCTCGTCGGCTGGCAGGCGCCCCCCGGGGCGCGCTCCATG
ACACCATGCAGCTGTGGCAGCTCGGACCTTTACTTGGTCACGAGACATGCTGATGTCATT
CCGGTGCGCCGGCGAGGCGACAGCAGGGGAAGTCTACTCTCCCCCAGGCCCGTCTCCTAC
CTGAAGGGCTCCTCGGGTGGTCCATTGCTTTGCCCTTCGGGGCACGTCGTGGGCGTCTTC
CGGGCTGCTGTGTGCACCCGGGGGGTCGCGAAGGCGGTGGACTTCATACCCGTTGAGTCT
ATGGAAACTACCATGCGGTCTCCGGTCTTCACAGACAACTCATCCCCCCCGGCTGTACCG
CAGACATTCCAAGTGGCACATCTGCACGCTCCTACTGGCAGCGGCAAGAGCACTAAAGTG
CCGGCTGCGTATGCAGCCCAAGGGTACAAGGTGCTCGTCCTGAACCCGTCCGTTGCCGCC
ACCTTAGGGTTTGGGGCGTATATGTCCAAGGCACACGGTATCGACCCTAACATCAGAACT
GGGGTAAGGACCATTACCACGGGCGGCTCCATTACGTACTCCACCTATGGCAAGTTCCTT
GCCGACGGTGGCTGCTCCGGGGGCGCCTATGACATCATAATATGTGATGAGTGCCACTCA
ACTGACTCGACTACCATCTTGGGCATCGGCACAGTCCTGGACCAAGCGGAGACGGCTGGA
GCGCGGCTTGTCGTGCTCGCCACCGCTACACCTCCGGGATCGGTTACCGTGCCACACCCC
AATATCGAGGAAATAGGCCTGTCCAACAATGGAGAGATCCCCTTCTATGGCAAAGCCATC
CCCATTGAGGCCATCAAGGGGGGGAGGCATCTCATTTTCTGCCATTCCAAGAAGAAATGT
GACGAGCTCGCCGCAAAGCTGACAGGCCTCGGACTGAATGCTGTAGCATATTACCGGGGC
CTTGATGTGTCCGTCATACCGCCTATCGGAGACGTCGTTGTCGTGGCAACAGACGCTCTA
ATGACGGGTTTCACCGGCGATTTTGACTCAGTGATCGACTGCAACACATGTGTCACCCAG
ACAGTCGACTTCAGCTTGGATCCCACCTTCACCATTGAGACGACGACCGTGCCCCAAGAC
GCGGTGTCGCGCTCGCAACGGCGAGGTAGAACTGGCAGGGGTAGGAGTGGCATCTACAGG
TTTGTGACTCCAGGAGAACGGCCCTCGGGCATGTTCGATTCTTCGGTCCTGTGTGAGTGC
TATGACGCGGGCTGTGCTTGGTATGAGCTCACGCCCGCTGAGACCTCGGTTAGGTTGCGG
GCTTACCTAAATACACCAGGGTTGCCCGTCTGCCAGGACCATCTGGAGTTCTGGGAGAGC
GTCTTCACAGGCCTCACCCACATAGATGCCCACTTCCTGTCCCAGACTAAACAGGCAGGA
GACAACTTTCCTTACCTGGTGGCATATCAAGCTACAGTATGCGCCAGGGCTCAAGCTCCA
CCTCCATCGTGGGACCAAATGTGGAAGTGTCTCATACGGCTGAAACCTACACTGCACGGG
CCAACACCCCTGCTGTATAGGCTAGGAGCCGTCCAAAATGAGGTCATCCTCACACACCCC
ATAACTAAATACATCATGGCATGCATGTCGGCTGACCTGGAGGTCGTCACTAGCACCTGG
GTGCTGGTAGGCGGAGTCCTTGCAGCTTTGGCCGCATATTGCCTGACGACAGGCAGTGTG
GTCATTGTGGGCAGGATCATCTTGTCCGGGAAGCCAGCTGTCGTTCCCGACAGGGAAGTC
CTCTACCAGGAGTTCGATGAGATGGAAGAGTGTGCCTCACAACTTCCTTACATCGAGCAG
GGAATGCAGCTCGCCGAGCAATTTAAGCAAAAGGCGCTCGGGTTGTTGCAAACGGCCACC
AAGCAAGCGGAGGCTGCTGCTCCCGTGGTGGAGTCCAAGTGGCGAGCCCTTGAGACCTTC
TGGGCGAAGCACATGTGGAATTTCATCAGCGGGATACAGTACCTAGCAGGCTTATCCACT
CTGCCTGGGAACCCCGCGATAGCATCATTGATGGCATTTACAGCTTCTATCACTAGCCCG
CTCACCACCCAAAACACCCTCCTGTTTAACATCTTGGGGGGATGGGTGGCTGCCCAACTC
GCTCCTCCCAGCGCTGCGTCAGCTTTCGTGGGCGCCGGCATCGCCGGAGCGGCTGTTGGC
AGCATAGGCCTTGGGAAGGTGCTCGTGGACATCTTGGCGGGCTATGGGGCAGGGGTAGCC
GGCGCACTCGTGGCCTTTAAGGTCATGAGCGGCGAGGTGCCCTCCACCGAGGACCTGGTC
AACTTACTCCCTGCCATCCTCTCTCCTGGTGCCCTGGTCGTCGGGGTCGTGTGCGCAGCA
ATACTGCGTCGGCACGTGGGCCCGGGAGAGGGGGCTGTGCAGTGGATGAACCGGCTGATA
GCGTTCGCTTCGCGGGGTAACCACGTCTCCCCCACGCACTATGTGCCTGAGAGCGACGCT
GCAGCACGTGTCACTCAGATCCTCTCTAGCCTTACCATCACTCAACTGCTGAAGCGGCTT
CACCAGTGGATTAATGAGGACTGCTCTACGCCATGCTCCGGCTCGTGGCTAAGGGATGTT
TGGGATTGGATATGCACGGTGTTGACTGACTTCAAGACCTGGCTCCAGTCCAAGCTCCTG
CCGCGGTTACCGGGAGTCCCTTTCCTGTCATGCCAACGCGGGTACAAGGGAGTCTGGCGG
GGGGACGGCATCATGCAAACCACCTGCCCATGTGGAGCACAGATCGCCGGACATGTCAAA
AACGGTTCCATGAGGATCGTAGGGCCTAGAACCTGCAGCAACACGTGGCACGGAACGTTC
CCCATCAACGCATACACCACGGGACCCTGCACACCCTCCCCGGCGCCCAACTATTCCAGG
GCGCTATGGCGGGTGGCTGCTGAGGAGTACGTGGAGGTTACGCGTGTGGGAGATTTCCAC
TACGTGACGGGCATGACCACTGACAACGTAAAGTGCCCATGCCAGGTTCCGGCCCCCGAA
TTCTTCACGGAGGTGGATGGAGTGCGGTTGCACAGGTACGCTCCGGCGTGCAAACCTCTC
CTACGGGAGGACGTCACGTTCCAGGTCGGGCTCAACCAATACTTGGTCGGGTCGCAGCTC
CCATGCGAGCCCGAACCGGACGTAACAGTGCTTACTTCCATGCTCACCGATCCCTCCCAC
ATTACAGCAGAGACGGCTAAGCGTAGGCTGGCTAGAGGGTCCCCCCCCTCTTTAGCCAGC
TCATCAGCTAGCCAGTTGTCTGCGCCTTCTTTGAAGGCGACATGCACTACCCACCATGAC
TCCCCGGACGCTGACCTCATCGAGGCCAACCTCTTGTGGCGGCAGGAGATGGGCGGAAAC
ATCACTCGCGTGGAGTCAGAGAATAAGGTAGTAATTCTGGACTCTTTCGAACCGCTTCAC
GCGGAGGGGGATGAGAGGGAGATATCCGTCGCGGCGGAGATCCTGCGAAAATCCAGGAAG
TTCCCCTCAGCGTTGCCCATATGGGCACGCCCGGACTACAATCCTCCACTGCTAGAGTCC
TGGAAGGACCCGGACTACGTCCCTCCGGTGGTACACGGATGCCCATTGCCACCTACCAAG
GCTCCTCCAATACCACCTCCACGGAGAAAGAGGACGGTTGTCCTGACAGAATCCAATGTG
TCTTCTGCCTTGGCGGAGCTCGCCACTAAGACCTTCGGTAGCTCCGGATCGTCGGCCGTT
GATAGCGGCACGGCGACCGCCCTTCCTGACCTGGCCTCCGACGACGGTGACAAAGGGTCC
GACGTTGAGTCGTACTCCTCCATGCCCCCCCTTGAAGGGGAGCCGGGGGACCCCGATCTC
AGCGACGGGTCTTGGTCTACCGTGAGTGAGGAGGCTAGTGAGGACGTCGTCTGCTGCTCA
ATGTCCTATACGTGGACAGGCGCCCTGATCACGCCATGCGCTGCGGAGGAAAGTAAGCTG
CCCATCAACCCGTTGAGCAACTCTTTGCTGCGTCACCACAACATGGTCTACGCCACAACA
TCCCGCAGCGCAAGCCTCCGGCAGAAGAAGGTCACCTTTGACAGATTGCAAGTCCTGGAT
GACCATTACCGGGACGTGCTCAAGGAGATGAAGGCGAAGGCGTCCACAGTTAAGGCTAAG
CTTCTATCTATAGAGGAGGCCTGCAAGCTGACGCCCCCACATTCGGCCAAATCCAAATTT
GGCTATGGGGCAAAGGACGTCCGGAACCTATCCAGCAGGGCCGTTAACCACATCCGCTCC
GTGTGGGAGGACTTGCTGGAAGACACTGAAACACCAATTGACACCACCATCATGGCAAAA
AGTGAGGTTTTCTGCGTCCAACCAGAGAAGGGAGGCCGCAAGCCAGCTCGCCTTATCGTA
TTCCCAGACCTGGGAGTTCGTGTATGCGAGAAGATGGCCCTTTACGACGTGGTCTCCACC
CTTCCTCAGGCCGTGATGGGCTCCTCATACGGATTTCAATACTCCCCCAAGCAGCGGGTC
GAGTTCCTGGTGAATACCTGGAAATCAAAGAAATGCCCTATGGGCTTCTCATATGACACC
CGCTGTTTTGACTCAACGGTCACTGAGAGTGACATTCGTGTTGAGGAGTCAATTTACCAA
TGTTGTGACTTGGCCCCCGAGGCCAGACAGGCCATAAGGTCGCTCACGGAGCGGCTTTAC
ATCGGGGGTCCCCTGACTAACTCAAAAGGGCAGAACTGCGGTTATCGCCGGTGCCGCGCA
AGTGGCGTGCTGACGACTAGCTGCGGTAATACCCTCACATGTTACTTGAAGGCCACTGCG
GCCTGTCGAGCTGCAAAGCTCCAGGACTGCACGATGCTCGTGAACGGAGACGACCTTGTC
GTTATCTGTGAAAGCGCGGGAACCCAGGAGGATGCGGCGGCCCTACGAGCCTTCACGGAG
GCTATGACTAGGTACTCCGCCCCCCCCGGGGATCCGCCCCAACCAGAATACGACCTGGAG
CTGATAACATCATGTTCCTCCAATGTGTCAGTCGCGCACGATGCATCTGGCAAAAGGGTA
TACTACCTCACCCGTGACCCCACCACCCCCCTTGCACGGGCTGCGTGGGAGACAGCTAGA
CACACTCCAATCAACTCTTGGCTAGGCAATATCATCATGTATGCGCCCACCCTATGGGCA
AGGATGATTCTGATGACTCACTTTTTCTCCATCCTTCTAGCTCAAGAGCAACTTGAAAAA
GCCCTGGATTGTCAGATCTACGGGGCCTGCTACTCCATTGAGCCACTTGACCTACCTCAG
ATCATTGAACGACTCCATGGTCTTAGCGCATTTACACTCCACAGTTACTCTCCAGGTGAG
ATCAATAGGGTGGCTTCATGCCTCAGGAAACTTGGGGTACCACCCTTGCGAACCTGGAGA
CATCGGGCCAGAAGTGTCCGCGCTAAGCTACTGTCCCAGGGGGGGAGGGCCGCCACTTGT
GGCAGATACCTCTTTAACTGGGCAGTAAGGACCAAGCTTAAACTCACTCCAATCCCGGCT
GCGTCCCAGCTGGACTTGTCCGGCTGGTTCGTCGCTGGTTACAGCGGGGGAGACATATAT
CACAGCCTGTCTCGTGCCCGACCCCGCTGGTTTCCGTTGTGCCTACTCCTACTTTTTGTA
GGGGTAGGCATTTACCTGCTCCCCAACCGATGA
PF01543
HCV_capsid
PF01542
HCV_core
PF01539
HCV_env
PF01560
HCV_NS1
PF01538
HCV_NS2
PF01006
HCV_NS4a
PF01001
HCV_NS4b
PF01506
HCV_NS5a
PF08300
HCV_NS5a_1a
PF08301
HCV_NS5a_1b
PF02907
Peptidase_S29
PF00998
RdRP_3
component
viral capsid
component
virion
component
viral envelope
function
hydrolase activity
function
nucleotide binding
function
purine nucleotide binding
function
peptidase activity
function
helicase activity
function
adenyl nucleotide binding
function
transferase activity
function
nucleotidyltransferase activity
function
binding
function
ATP binding
function
transferase activity, transferring phosphorus-containing groups
function
serine-type peptidase activity
function
catalytic activity
function
nucleic acid binding
function
RNA-directed RNA polymerase activity
function
RNA binding
function
structural molecule activity
process
viral infectious cycle
process
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
process
viral genome replication
process
macromolecule metabolism
process
protein metabolism
process
cellular protein metabolism
process
proteolysis
process
interaction between organisms
process
interspecies interaction between organisms
process
transcription
process
physiological process
process
symbiosis, encompassing mutualism through parasitism
process
interaction with host
process
metabolism
process
virus-host interaction
process
viral life cycle
process
cellular metabolism
process
transformation of host cell by virus
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All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/drugbank_small.nt
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