Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/1019"

Predicate	Value (sorted: none)
rdf:type	?:Evidence
rdf:type	?:Item
rdfs:label	"evidence_1865"
?:Evidence_type	?:EV_EX_Met_Enz_Inhibit_Cyp450_Hum_Microsome
?:Evidence_enzyme_system	""
dc:creator	"boycer"
dc:date	"01132010"
?:content	"Enzyme system: human liver microsomes: NADPH added: yes substrate used: midazolam reaction: midazolam 1'hydroxylation IC50 > 200micM (see Table 3) Quote: Pantoprazole showed a stronger inhibitory effect (Ki 22mM) on midazolam 1'-hydroxylation than omeprazole (Ki 42micM), esomeprazole (Ki 47micM), and rabeprazole (Ki 51micM). The IC50 of lansoprazole was over 200 M."
rdfs:seeAlso	?:15258107

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl

The resource appears as object in one triple:

{ lansoprazole_does_not_inhibit_cyp3a4, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1865 }

Context graph