Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/1191"

Predicate	Value (sorted: none)
rdf:type	?:Evidence
rdf:type	?:Item
rdfs:label	"evidence_1510"
?:Evidence_type	?:EV_CT_Pharmacokinetic
?:Evidence_enzyme_system	""
dc:creator	"boycer"
dc:date	"06/15/2009 16:12:54"
?:content	"Enzyme system: human liver microsomes NADPH added: yes Quote: Metabolism of clozapine to stable and protein-reactive metabolites by human liver. Chromatographic analysis of the microsomal incubation supernatants showed that clozapine was metabolized to five metabolites: desmethylclozapine, clozapine N-oxide, 7-hydroxyclozapine and two un- identified metabolites (fig 1). The CYP2D6 genotype did not affect the formation of these metabolites (table 2)."
rdfs:seeAlso	?:7891353

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl

The resource appears as object in one triple:

{ clozapine_has_metabolite_desmethylclozapine, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1510 }

Context graph