Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/1199"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label |
"evidence_1419"
|
| rdf:type | |
| ?:Evidence_assump_list_id |
"208"
|
| ?:Evidence_enzyme_system | |
| ?:Evidence_type | |
| ?:claim_assumed_valid_for_evidence_application_evidence_1419 | |
| ?:content |
"Enzyme system: human liver microsomes
NADPH added: yes
inhibitor used: ketoconazole
reaction:
clarithromycin --> 14-(R)-hydroxylase-clarithromycin clarithromycin --> 14-N-demethylase-clarithromycin
description: clarithromycin oxidative metabolism was nearly completely wiped out by the addition of this selective inhibitor"
|
| dc:creator | |
| dc:date |
"10/20/2007 08:43:35"
|
| rdfs:seeAlso |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl
The resource appears as object in one triple:
{ cyp3a4_controls_formation_of_14-hydroxyclarithromycin, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1419 }