Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/1216"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label |
"evidence_1715"
|
| rdf:type | |
| ?:Evidence_enzyme_system | |
| ?:Evidence_type | |
| ?:content |
""lovastatin is a lactone which is readily hydrolyzed in vivo to the corresponding beta-hydroxyacid, a potent inhibitor of HMG-CoA reductase. Inhibition of HMG-CoA reductase is the basis for an assay in pharmacokinetic studies of the beta-hydroxyacid metabolites (active inhibitors) and, following base hydrolysis, active plus latent inhibitors (total inhibitors) in plasma following administration of lovastatin.
""
|
| dc:creator | |
| dc:date |
"09/28/2007 13:21:21"
|
| rdfs:seeAlso |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl
The resource appears as object in one triple:
{ lovastatin_has_metabolite_beta-hydroxy-lovastatin, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1715 }