Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/1254"

PredicateValue (sorted: default)
rdfs:label
"evidence_1592"
rdf:type
?:Evidence
?:Item
?:Evidence_enzyme_system
""
?:Evidence_type
?:EV_EX_Met_Enz_ID_Cyp450_Hum_Recom
?:content
"Enzyme system: recombinant human CYP3A5 enzymes in insect microsomes NADPH added: yes substrate used: atorvastatin acid and lactone reaction: atorvastatin acid-->para-hydroxy-atorvastatin atorvastatin lactone-->para-hydroxy-atorvastatin description: According to the authors, this enzyme system catalyzed the above reactions similar to that of the CYP3A4 recombinant enzyme system whose Km values ranged from 1.4micM/L for atorvastatin lactone-->para-hydroxy-atorvastatin to 29.7micM/L for the atorvastatin acid-->ortho-hydroxy-atorvastatin"
dc:creator
"boycer"
dc:date
"09/25/2007 08:44:00"
rdfs:seeAlso
?:11038166

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl

The resource appears as object in one triple:

{ cyp3a5_controls_formation_of_para-hydroxy-atorvastatin, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1592 }

Context graph