Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/1360"

Predicate	Value (sorted: default)
rdfs:label	"evidence_1706"
rdf:type	?:Evidence ?:Item
?:Evidence_assump_list_id	"234"
?:Evidence_enzyme_system	""
?:Evidence_type	?:EV_PK_DDI_NR
?:claim_assumed_valid_for_evidence_application_evidence_1706	?:erythromycin_in_viVo_selective_inhibitor_of_enzyme_cyp3a4
?:content	"Route of administration: oral study duration: multiple doses of QTP with or without concomitant erythromycin population: 19; 10 female and 9 male NOTE:no participants were tested for known CYP phenotypes ages:18-55 Quote: In presence of erythromycin, activity of CYP3A4 decreased significantly; for QTP, C(max), AUC(0-24), and t(1/2) increased significantly, CL decreased significantly, and variations in AUC(0-24) and CL showed, respectively, significant negative and positive correlation to that of CYP3A4 activity;"
dc:creator	"boycer"
dc:date	"06/16/2009 17:22:10"
rdfs:seeAlso	?:15834460

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl

The resource appears as object in one triple:

{ quetiapine_substrate_of_cyp3a4, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1706 }

Context graph