Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/1385"

PredicateValue (sorted: default)
rdfs:label
rdf:type
?:Evidence_enzyme_system
?:Evidence_type
?:content
""Metabolism and Drug Interactions Risperidone is extensively metabolized in the liver. The main metabolic pathway is through hydroxylation of risperidone to 9-hydroxyrisperidone by the enzyme, CYP 2D6. A minor metabolic pathway is through N-dealkylation. The main metabolite, 9-hydroxyrisperidone, has similar pharmacological activity as risperidone. Consequently, the clinical effect of the drug (e.g., the active moiety) results from the combined concentrations of risperidone plus 9-hydroxyrisperidone.""
dc:creator
dc:date
"06/15/2009 15:33:10"
rdfs:seeAlso

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl

The resource appears as object in one triple:

{ risperidone_primary_total_clearance_mechanism_Metabolic_Clearance, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1769 }

Context graph