Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/1447"
| Predicate | Value (sorted: none) |
|---|---|
| rdf:type | |
| rdf:type | |
| rdfs:label | |
| ?:Evidence_type | |
| ?:Evidence_dose | |
| ?:Evidence_enzyme_system | |
| ?:Evidence_value | |
| dc:creator | |
| dc:date |
"06/22/2009 10:55:54"
|
| ?:content |
"route of administration: oral (parent drug)
study duration: Plasma profiles were obtained: 1) after a single 100 mg oral dose of [NON-XR] bupropion hydrochloride, 2) following administration of 100 mg 8-hourly for 14 days and 3) again after a single 100 mg dose 14 days later.
population: 8 healthy, non-smoking, male subjects
tested for known CYP450 polymorphisms? NO
ages: 22 - 42
C_max of HYDROXYBUPROPION @ 300mg/day of NON-XR bupropion for 14 days: 4.2micM/L (OCCASION 2, Table 2, 306U)
4.2micM/1L X 1M/10^6micM X 256.749g/1M = 0.001g/L"
|
| rdfs:seeAlso |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl
The resource appears as object in one triple:
{ hydroxybupropion_maximum_concentration_continuous_value, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1958 }