Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/37"

Predicate	Value (sorted: none)
rdf:type	?:Evidence
rdf:type	?:Item
rdfs:label	"evidence_1381"
?:Evidence_type	?:EV_PK_DDI_NR
?:Evidence_assump_list_id	"9"
?:Evidence_enzyme_system	""
?:claim_assumed_valid_for_evidence_application_evidence_1381	?:warfarin_primary_total_clearance_enzyme_cyp2c9
dc:creator	"boycer"
dc:date	"09/27/2007 11:44:51"
?:content	"Route of administration: fluconazole oral; warfarin - IV study duration: phase 1 - 8 days of .75mg/kg warfarin alone; phase 2 (21 days later) 14 days of .75mg/kg q.d. AND 400mg q.d. of fluconazole population: 6 male ages: 23-29 description: formation of 6- and 7-OH-(s)-warfarin decreased by 70%; this reaction is considered primarily catalyzed by CYP2C9. There was also a notable increase in AUC of (S)-warfarin (mean AUC_i/AUC=7.633)"
rdfs:seeAlso	?:8801057

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl

The resource appears as object in one triple:

{ fluconazole_inhibits_cyp2c9, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1381 }

Context graph