Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/499"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label |
"evidence_1741"
|
| rdf:type | |
| ?:Evidence_assump_list_id |
"95"
|
| ?:Evidence_enzyme_system | |
| ?:Evidence_type | |
| ?:Evidence_value |
"0.0002255"
|
| ?:claim_assumed_valid_for_evidence_application_evidence_1741 | |
| ?:content |
"Enzyme system: human liver microsome and recombinant human enzymes in insect cells
NADPH added: yes
substrate used: testosterone
reaction: testosterone-->6beta-OH-testosterone
This study showed significant inhibition of 6beta-OH-testosterone in enzyme systems incubated with diltiazem. IC50 = 5.0microM, Ki = .5microM"
|
| dc:creator | |
| dc:date |
"07/03/2007 09:31:31"
|
| rdfs:seeAlso |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl
The resource appears as object in one triple:
{ diltiazem_inhibition_constant_cyp3a4, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1741 }