Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/730"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label | |
| rdf:type | |
| ?:Evidence_enzyme_system | |
| ?:Evidence_numb_subjects | |
| ?:Evidence_object_dose | |
| ?:Evidence_precip_dose | |
| ?:Evidence_type | |
| ?:Evidence_value |
"9.16"
|
| ?:content |
"In a double-blind clinical pharmacokinetic-pharmacodynamic study, administration of triazolam (0.125 mg) preceded by ketoconazole, compared to triazolam preceded by placebo, produced a nearly 9-fold reduction in apparent oral clearance of triazolam (41 vs. 337 ml/min) and a 4-fold prolongation of half-life (13.5 vs. 3.4 hr).
NOTE: AUC increase values take from table 3"
|
| dc:creator | |
| dc:date |
"06/05/2007 07:46:02"
|
| rdfs:seeAlso |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl
The resource appears as object in one triple:
{ ketoconazole_increases_auc_triazolam, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1565 }