Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/891"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label | |
| rdf:type | |
| ?:Evidence_enzyme_system | |
| ?:Evidence_object_dose | |
| ?:Evidence_precip_dose | |
| ?:Evidence_type | |
| ?:Evidence_value | |
| ?:content |
"route of administration: oral (indinavir)
study duration: not mentioned (venlafaxine steady-state)
population: 9 healthy volunteers
tested for known CYP450 polymorphisms?
NO
ages: not mentioned
Quote:
In a study of 9 healthy volunteers, venlafaxine administered under steady-state conditions at 150 mg/day resulted in a 28% decrease in the AUC of a single 800 mg oral dose of indinavir and a 36% decrease in indinavir Cmax. Indinavir did not affect the pharmacokinetics of venlafaxine and ODV. The clinical significance of this finding is unknown."
|
| dc:creator | |
| dc:date |
"02/16/2012 21:19:58"
|
| rdfs:seeAlso |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl
The resource appears as object in one triple:
{ indinavir_increases_auc_venlafaxine, <http://purl.org/swan/1.2/swan-commons#citesAsRefutingEvidence>, evidence_1096 }