Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/903"

Predicate	Value (sorted: default)
rdfs:label	"evidence_1982"
rdf:type	?:Evidence ?:Item
?:Evidence_assump_list_id	"162"
?:Evidence_enzyme_system	""
?:Evidence_type	?:EV_EX_Met_Enz_ID_Cyp450_Hum_Microsome_Chem
?:claim_assumed_valid_for_evidence_application_evidence_1982	?:quinidine_in_vitro_selective_inhibitor_of_enzyme_cyp2d6
?:content	"Enzyme system: human liver microsomes: NADPH added: yes inhibitor used: quinidine reaction: venlafaxine --> O-desmethylvenlafaxine Quote: "All six SSRIs [including quinidine] inhibited the formation of ODV with PX being the most potent and DES being the least potent (Table 3)." K_i for quinidine vs O-desmethylvenlafaxine formation: 0.04micM"
dc:creator	"boycer"
dc:date	"06/20/2009 14:31:52"
rdfs:seeAlso	?:10192828

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl

The resource appears as object in one triple:

{ cyp2d6_controls_formation_of_O-desmethylvenlafaxine, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1982 }

Context graph