Local view for "https://dbmi-icode-01.dbmi.pitt.edu/dikb/resource/Evidence/904"
Predicate | Value (sorted: default) |
---|---|
rdfs:label |
"evidence_1006"
|
rdf:type | |
?:Evidence_assump_list_id |
"163"
|
?:Evidence_enzyme_system | |
?:Evidence_type | |
?:claim_assumed_valid_for_evidence_application_evidence_1006 | |
?:content |
"Enzyme system: human liver microsomes:
NADPH added: yes
inhibitor used: paroxetine
reaction: venlafaxine --> O-desmethylvenlafaxine
Quote:
"All six SSRIs inhibited the formation of ODV with PX being the most potent and DES being the least potent (Table 3)."
K_i for paroxetine vs O-desmethylvenlafaxine formation: 0.17micM"
|
dc:creator | |
dc:date |
"06/20/2009 14:33:21"
|
rdfs:seeAlso |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines/dikb.ttl
The resource appears as object in one triple:
{ cyp2d6_controls_formation_of_O-desmethylvenlafaxine, <http://purl.org/swan/1.2/swan-commons#citesAsSupportingEvidence>, evidence_1006 }