Triples with object Enzyme system: human liver microsomes NADPH added: yes (a dehydrogenase generating system) probe reaction: triazolam hydroxylation Quote: CYP3A. CT and metabolites all were very weak or negligible inhibitors of CYP3A, as indicated by triazolam hydroxylation. None of the compounds (at 100micM) produced more than 50% inhibition. Fluvoxamine and nefazodone were moderately strong inhibitors (von Moltke et al., 1996b, 1999c).